iPTMnet Report for Q9UL46 (PSME2)
Protein Information
UniProt AC / UniProt ID | Q9UL46 / PSME2_HUMAN |
Protein Name | Proteasome activator complex subunit 2 |
Gene Name | Name: PSME2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UL46 |
PRO Name | proteasome activator complex subunit 2 (human) |
Definition | A proteasome activator complex subunit 2 that is encoded in the genome of human. |
Short Label | hPSME2 |
Category | organism-gene |
Q9UL46 (PSME2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378 | ||
K3 | Methylation | score1 | PhosphoSitePlus | |||
K3 | Ubiquitination | score1 | PhosphoSitePlus | |||
R8 | Methylation | score1 | PhosphoSitePlus | |||
S10 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19413330, 23186163, 20068231 | ||
K15 | Ubiquitination | score1 | PhosphoSitePlus | |||
K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
S102 | Phosphorylation | score1 | PhosphoSitePlus | |||
K108 | Ubiquitination | score1 | PhosphoSitePlus | |||
K115 | Acetylation | score1 | IEDB | 34357683 | ||
K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
K117 | Acetylation | score1 | IEDB | 34357683 | ||
K145 | Ubiquitination | score1 | PhosphoSitePlus | |||
T162 | Phosphorylation | score0 | HPRD | 20068231 | ||
K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
K180 | Acetylation | score1 | PhosphoSitePlus | |||
Y187 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y199 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y217 | Phosphorylation | score1 | PhosphoSitePlus | |||
K235 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y239 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | V2 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
S10 | C10 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S102 | F102 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K180 | N180 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
Y199 | C199 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y239 | C239 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] |