iPTMnet Report for Q9UKY1 (ZHX1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKY1 / ZHX1_HUMAN
Protein Name Zinc fingers and homeoboxes protein 1
Gene Name Name: ZHX1
Organism Homo sapiens (Human)

PRO ID PR:Q9UKY1
DAG View
PRO Name zinc fingers and homeoboxes protein 1 (human)
Definition A zinc fingers and homeoboxes protein 1 that is encoded in the genome of human.
Short Label hZHX1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKY1 (ZHX1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
T9 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S26 Phosphorylation phospho.ELM 18669648
T36 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 24275569
S45 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S47 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S48 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 24275569
N99 N-Glycosylation GlyGen 29671580
S156 Phosphorylation PhosphoSitePlus
K159 Sumoylation PhosphoSitePlus
S202 Phosphorylation PhosphoSitePlus   UniProt 23186163
K210 Sumoylation PhosphoSitePlus
S226 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 29485866, 35289036, 30620550, 29237092, 20068230
S227 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 29485866, 35289036, 30620550, 29237092, 20068230
S228 O-Glycosylation GlyGen 23301498, 33214551, 35254053, ...30379171, 32574038, 32938750, 34019948, 30059200, 35132862, 31492838, 29485866, 35289036, 30620550, 29237092, 20068230
S232 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 29485866, 35289036, 30620550, 29237092, 20068230
T252 Phosphorylation IEDB 35494241
Y289 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
Y303 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
T437 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 29485866, 35289036, 30620550, 29237092, 20068230
T440 O-Glycosylation GlyGen 32574038
K441 Sumoylation PhosphoSitePlus
T444 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 29485866, 35289036, 30620550, 29237092, 20068230
T449 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 29485866, 35289036, 30620550, 29237092, 20068230
S450 O-Glycosylation GlyGen   PhosphoSitePlus 23301498, 33214551, 30379171, ...32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 29485866, 35289036, 30620550, 29237092, 20068230
S452 O-Glycosylation GlyGen 23301498, 33214551, 30379171, ...32574038, 35254053, 34019948, 30059200, 35132862, 31492838, 29485866, 35289036, 30620550, 29237092, 20068230
K454 Sumoylation PhosphoSitePlus
K485 Sumoylation PhosphoSitePlus
T568 Phosphorylation P24941 (CDK2) PhosphoSitePlus 18847512
S591 Phosphorylation PhosphoSitePlus
S635 Phosphorylation PhosphoSitePlus
S639 Phosphorylation PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
T647 Phosphorylation PhosphoSitePlus
S648 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 15302935, 19690332
S660 Phosphorylation PhosphoSitePlus
T668 Phosphorylation PhosphoSitePlus
T682 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S686 Phosphorylation PhosphoSitePlus
S739 Phosphorylation PhosphoSitePlus
S774 Phosphorylation PhosphoSitePlus   UniProt 23186163
K779 Ubiquitination PhosphoSitePlus
T780 Phosphorylation PhosphoSitePlus
T782 Phosphorylation PhosphoSitePlus
Y789 Phosphorylation PhosphoSitePlus
K793 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD 18452278
T8 Phosphorylation HPRD 18452278
T9 Phosphorylation HPRD 18669648, 18452278
S26 Phosphorylation HPRD 18669648
S45 Phosphorylation HPRD 18669648, 18452278
S47 Phosphorylation HPRD 18669648, 18452278
S48 Phosphorylation HPRD 18669648, 18452278
N99 N-Glycosylation PRO 29671580
S202 Phosphorylation HPRD 18452278
Y289 Phosphorylation HPRD 18083107
Y303 Phosphorylation HPRD 18083107
S635 Phosphorylation HPRD 19413330
S639 Phosphorylation HPRD 19413330
S640 Phosphorylation HPRD 18452278
S648 Phosphorylation HPRD 19413330, 18669648, 15302935, ...18452278
T682 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T8 A8 Biomuta DOID:1324 / lung cancer [ cosmic ]
S202 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S226 I226 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S232 C232 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y289 C289 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
T444 A444 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
K454 I454 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S660 I660 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S660 R660 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T780 N780 Biomuta DOID:363 / uterine cancer [ icgc ]