iPTMnet Report for Q9UKN8 (GTF3C4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKN8 / TF3C4_HUMAN
Protein Name General transcription factor 3C polypeptide 4
Gene Name Name: GTF3C4
Organism Homo sapiens (Human)

PRO ID PR:Q9UKN8
DAG View
PRO Name general transcription factor 3C polypeptide 4 (human)
Definition A general transcription factor 3C polypeptide 4 that is encoded in the genome of human.
Short Label hGTF3C4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKN8 (GTF3C4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
S19 Phosphorylation PhosphoSitePlus   UniProt 23186163
K33 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
R149 Methylation PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
K165 Methylation PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
Y217 Phosphorylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
T355 Phosphorylation PhosphoSitePlus
K364 Ubiquitination PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
Y380 Phosphorylation PhosphoSitePlus
Y383 Phosphorylation PhosphoSitePlus
Y398 Phosphorylation PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K460 Ubiquitination PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
C485 Methylation IEDB 31844290
K551 Ubiquitination PhosphoSitePlus
K563 Ubiquitination PhosphoSitePlus
T571 Phosphorylation HPRD 20068231
K598 Ubiquitination PhosphoSitePlus
T600 Phosphorylation PhosphoSitePlus
S604 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 23186163
S611 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 21406692, ...23186163, 17081983, 20058876, 19664994, 19664995, 18452278, 19651622, 15302935, 18669648, 19690332, 19415658, 20068231
K629 Ubiquitination PhosphoSitePlus
K633 Ubiquitination PhosphoSitePlus
S640 Phosphorylation PhosphoSitePlus
K641 Ubiquitination PhosphoSitePlus
S652 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 18452278
T656 Phosphorylation PhosphoSitePlus
K668 Ubiquitination PhosphoSitePlus
K740 Ubiquitination PhosphoSitePlus
K760 Ubiquitination PhosphoSitePlus
S793 Phosphorylation IEDB 35494241
K807 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K137 E137 Biomuta DOID:363 / uterine cancer [ cosmic ]
K156 N156 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y380 C380 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S611 L611 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K641 E641 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K740 R740 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K807 N807 Biomuta DOID:9256 / colorectal cancer [ cosmic ]