Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UKA2 / FBXL4_HUMAN
Protein Name F-box/LRR-repeat protein 4
Gene Name Name: FBXL4
Synonyms:FBL4,FBL5;
Organism Homo sapiens (Human)

PRO ID PR:Q9UKA2
DAG View
PRO Name F-box/LRR-repeat protein 4 (human)
Definition An F-box/LRR-repeat protein 4 that is encoded in the genome of human.
Short Label hFBXL4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UKA2 (FBXL4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T34 O-Glycosylation GlyGen 30379171
K115 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
C194 Methylation IEDB 31844290
T202 Phosphorylation PhosphoSitePlus
T238 Phosphorylation PhosphoSitePlus
S239 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
Y467 Phosphorylation PhosphoSitePlus
S472 Phosphorylation PhosphoSitePlus
K537 Ubiquitination PhosphoSitePlus
C595 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
C194 Y194 Biomuta DOID:1319 / brain cancer [ icgc ]
T202 K202 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S239 L239 Biomuta DOID:4159 / skin cancer [ cosmic ]
S460 R460 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S472 G472 Biomuta DOID:3571 / liver cancer [ cosmic ]