iPTMnet Report for Q9UKA2 (FBXL4)
Protein Information
UniProt AC / UniProt ID | Q9UKA2 / FBXL4_HUMAN |
Protein Name | F-box/LRR-repeat protein 4 |
Gene Name | Name: FBXL4 Synonyms:FBL4,FBL5; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UKA2 |
PRO Name | F-box/LRR-repeat protein 4 (human) |
Definition | An F-box/LRR-repeat protein 4 that is encoded in the genome of human. |
Short Label | hFBXL4 |
Category | organism-gene |
Q9UKA2 (FBXL4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T34 | O-Glycosylation | score1 | GlyGen | 30379171 | ||
K115 | Ubiquitination | score1 | PhosphoSitePlus | |||
K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
C194 | Methylation | score1 | IEDB | 31844290 | ||
T202 | Phosphorylation | score1 | PhosphoSitePlus | |||
T238 | Phosphorylation | score1 | PhosphoSitePlus | |||
S239 | Phosphorylation | score1 | PhosphoSitePlus | |||
S460 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y467 | Phosphorylation | score1 | PhosphoSitePlus | |||
S472 | Phosphorylation | score1 | PhosphoSitePlus | |||
K537 | Ubiquitination | score1 | PhosphoSitePlus | |||
C595 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
C194 | Y194 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
T202 | K202 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S239 | L239 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S460 | R460 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S472 | G472 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |