iPTMnet Report for Q9UK58 (CCNL1)
Protein Information
UniProt AC / UniProt ID | Q9UK58 / CCNL1_HUMAN |
Protein Name | Cyclin-L1 |
Gene Name | Name: CCNL1 ORFNames:BM-001,UNQ530/PRO1073; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UK58 |
PRO Name | cyclin-L1 (human) |
Definition | A cyclin-L1 that is encoded in the genome of human. |
Short Label | hCCNL1 |
Category | organism-gene |
Q9UK58 (CCNL1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T30 | Phosphorylation | score1 | PhosphoSitePlus | |||
T32 | Phosphorylation | score1 | PhosphoSitePlus | |||
T33 | Phosphorylation | score1 | PhosphoSitePlus | |||
T37 | Phosphorylation | score1 | PhosphoSitePlus | |||
S65 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 15302935, 18220336 | ||
T67 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18220336 | ||
S166 | Phosphorylation | score1 | PhosphoSitePlus | |||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y289 | Phosphorylation | score1 | PhosphoSitePlus | |||
T325 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 17081983 | ||
S329 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
T330 | Phosphorylation | score1 | PhosphoSitePlus | |||
S335 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 19690332, 20068231, ... | ||
S338 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 15302935, 17081983, ... | ||
S341 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S342 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648, 15302935 | ||
S352 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 21406692, 23186163, 18669648, ... | ||
S355 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 15302935, 18669648, 23186163 | ||
S372 | Phosphorylation | score1 | PhosphoSitePlus | |||
S374 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
Y376 | Phosphorylation | score1 | PhosphoSitePlus | |||
S401 | Phosphorylation | score1 | PhosphoSitePlus | |||
S403 | Phosphorylation | score1 | PhosphoSitePlus | |||
S405 | Phosphorylation | score1 | PhosphoSitePlus | |||
S417 | Phosphorylation | score1 | PhosphoSitePlus | |||
S419 | Phosphorylation | score1 | PhosphoSitePlus | |||
T421 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y422 | Phosphorylation | score1 | PhosphoSitePlus | |||
S424 | Phosphorylation | score1 | PhosphoSitePlus | |||
S445 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 20068231 | ||
K449 | Acetylation | score1 | PhosphoSitePlus | |||
K451 | Acetylation | score1 | PhosphoSitePlus | |||
S470 | Phosphorylation | score1 | PhosphoSitePlus | |||
R471 | Methylation | score1 | PhosphoSitePlus | |||
R473 | Methylation | score1 | PhosphoSitePlus | |||
K486 | Ubiquitination | score1 | PhosphoSitePlus | |||
K487 | Ubiquitination | score1 | PhosphoSitePlus | |||
S502 | Phosphorylation | score1 | PhosphoSitePlus | |||
S504 | Phosphorylation | score1 | PhosphoSitePlus | |||
K512 | Methylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S65 | Phosphorylation | score0 | HPRD | 15302935, 18452278 | ||
T325 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 17081983, ... | ||
S329 | Phosphorylation | score0 | HPRD | 19413330, 18669648, 17081983, ... | ||
T330 | Phosphorylation | score0 | HPRD | 17081983, 20068231 | ||
S335 | Phosphorylation | score0 | HPRD | 19413330, 19664995, 18452278, ... | ||
S338 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 18452278, ... | ||
S341 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 19664995, ... | ||
S342 | Phosphorylation | score0 | HPRD | 19413330, 17081983, 19664995, ... | ||
S352 | Phosphorylation | score0 | HPRD | 17322306, 18578522, 18767875, ... | ||
S355 | Phosphorylation | score0 | HPRD | 18669648, 15302935 | ||
S372 | Phosphorylation | score0 | HPRD | 19664995 | ||
S374 | Phosphorylation | score0 | HPRD | 20068231 | ||
S401 | Phosphorylation | score0 | HPRD | 19651622 | ||
S403 | Phosphorylation | score0 | HPRD | 19651622 | ||
S405 | Phosphorylation | score0 | HPRD | 19651622 | ||
S445 | Phosphorylation | score0 | HPRD | 19651622, 18767875, 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S65 | L65 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S65 | W65 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
Y289 | H289 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S355 | F355 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S355 | A355 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S419 | Y419 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
K449 | N449 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S470 | Y470 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
R471 | C471 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] | |
R471 | L471 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K487 | T487 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |