iPTMnet Report for Q9UK55 (SERPINA10)
Protein Information
UniProt AC / UniProt ID | Q9UK55 / ZPI_HUMAN |
Protein Name | Protein Z-dependent protease inhibitor precursor |
Gene Name | Name: SERPINA10 Synonyms:ZPI;ORFNames:UNQ707/PRO1358; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UK55 |
PRO Name | protein Z-dependent protease inhibitor (human) |
Definition | A protein Z-dependent protease inhibitor that is encoded in the genome of human. |
Short Label | hSERPINA10 |
Category | organism-gene |
Q9UK55 (SERPINA10) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N36 | N-Glycosylation | score2 | GlyGen UniProt | 19159218 | ||
S56 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 19824718, 20166139, 26091039, ... | ||
S61 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19824718, 20166139 | ||
N180 | N-Glycosylation | score2 | GlyGen UniProt | 16335952, 29741879, 29671580, ... | ||
N197 | N-Glycosylation | score4 | GlyGen UniProt | 20427285, 29391424 | ||
Y292 | Phosphorylation | score1 | PhosphoSitePlus | |||
N295 | N-Glycosylation | score4 | GlyGen UniProt | 16335952, 29741879, 20427285, ... | ||
T297 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
N36 | T36 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
S56 | I56 | Biomuta | DOID:1324 / lung cancer [ icgc ] | |
S61 | G61 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] | |
Y292 | N292 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |