Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UHX3 / AGRE2_HUMAN
Protein Name Adhesion G protein-coupled receptor E2 precursor
Gene Name Name: ADGRE2
Synonyms:EMR2;
Organism Homo sapiens (Human)

PRO ID PR:Q9UHX3
DAG View
PRO Name adhesion G protein-coupled receptor E2 (human)
Definition An adhesion G protein-coupled receptor E2 that is encoded in the genome of human.
Short Label hADGRE2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UHX3 (ADGRE2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N41 N-Glycosylation GlyGen 29741879
N111 N-Glycosylation GlyGen 29741879, 24190977
K284 Ubiquitination PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
T361 O-Glycosylation GlyGen 29351928
S364 O-Glycosylation GlyGen 29351928
Y670 Phosphorylation PhosphoSitePlus
T672 Phosphorylation PhosphoSitePlus
S674 Phosphorylation PhosphoSitePlus
T807 Phosphorylation PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
S811 Phosphorylation PhosphoSitePlus
K813 Ubiquitination PhosphoSitePlus
K818 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N41 I41 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
N41 K41 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S303 N303 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T361 K361 Biomuta DOID:1324 / lung cancer [ cosmic ]
S364 F364 Biomuta DOID:4159 / skin cancer [ cosmic ]
S674 F674 Biomuta DOID:4159 / skin cancer [ cosmic ]