iPTMnet Report for Q9UHE8 (STEAP1)
Protein Information
| UniProt AC / UniProt ID | Q9UHE8 / STEA1_HUMAN |
| Protein Name | STEAP1 protein |
| Gene Name | Name: STEAP1 Synonyms:PRSS24,STEAP; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UHE8 |
| PRO Name | metalloreductase STEAP1 (human) |
| Definition | A metalloreductase STEAP1 that is encoded in the genome of human. |
| Short Label | hSTEAP1 |
| Category | organism-gene |
DAG ViewQ9UHE8 (STEAP1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| Y27 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18578522 | ||
| K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K39 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K76 | Acetylation | score1 | IEDB | 34357683 | ||
| T160 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y178 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y188 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y219 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S221 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K329 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K332 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S337 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18077418 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K39 | R39 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K39 | I39 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| Y219 | C219 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S337 | Y337 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] |
