iPTMnet Report for Q9UHC1 (MLH3)
Protein Information
UniProt AC / UniProt ID | Q9UHC1 / MLH3_HUMAN |
Protein Name | DNA mismatch repair protein Mlh3 |
Gene Name | Name: MLH3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UHC1 |
PRO Name | DNA mismatch repair protein Mlh3 (human) |
Definition | A DNA mismatch repair protein Mlh3 that is encoded in the genome of human. |
Short Label | hMLH3 |
Category | organism-gene |
Q9UHC1 (MLH3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K128 | Ubiquitination | score1 | PhosphoSitePlus | |||
T147 | Phosphorylation | score1 | IEDB | 32357974 | ||
S188 | Phosphorylation | score1 | PhosphoSitePlus | |||
T335 | Phosphorylation | score1 | IEDB | 35494241 | ||
K380 | Ubiquitination | score1 | PhosphoSitePlus | |||
K414 | Ubiquitination | score1 | PhosphoSitePlus | |||
T422 | Phosphorylation | score1 | PhosphoSitePlus | |||
S424 | Phosphorylation | score1 | PhosphoSitePlus | |||
S425 | Phosphorylation | score1 | PhosphoSitePlus | |||
R600 | Methylation | score1 | PhosphoSitePlus | |||
T606 | Phosphorylation | score1 | PhosphoSitePlus | |||
T610 | Phosphorylation | score1 | PhosphoSitePlus | |||
K619 | Ubiquitination | score1 | PhosphoSitePlus | |||
K628 | Ubiquitination | score1 | PhosphoSitePlus | |||
K656 | Ubiquitination | score1 | PhosphoSitePlus | |||
K664 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y681 | Phosphorylation | score1 | PhosphoSitePlus | |||
T690 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y691 | Phosphorylation | score1 | PhosphoSitePlus | |||
S746 | Phosphorylation | score1 | PhosphoSitePlus | |||
S753 | Phosphorylation | score1 | PhosphoSitePlus | |||
K876 | Ubiquitination | score1 | PhosphoSitePlus | |||
K881 | Acetylation | score1 | PhosphoSitePlus | |||
S883 | Phosphorylation | score1 | PhosphoSitePlus | |||
K982 | Ubiquitination | score1 | PhosphoSitePlus | |||
T1062 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1128 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1188 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1208 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1243 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1256 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1257 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1258 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1413 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T147 | K147 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S188 | Y188 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
R600 | Q600 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
T610 | I610 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
K628 | T628 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y681 | H681 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S746 | R746 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S753 | Y753 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K876 | R876 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K881 | T881 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
S883 | F883 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |