iPTMnet Report for Q9UGU0 (TCF20)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UGU0 / TCF20_HUMAN
Protein Name Transcription factor 20
Gene Name Name: TCF20
Synonyms:KIAA0292,SPBP;
Organism Homo sapiens (Human)

PRO ID PR:Q9UGU0
DAG View
PRO Name transcription factor 20 (human)
Definition A transcription factor 20 that is encoded in the genome of human.
Short Label hTCF20
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UGU0 (TCF20) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S31 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S53 Phosphorylation PhosphoSitePlus
S55 Phosphorylation PhosphoSitePlus
R60 Methylation PhosphoSitePlus   UniProt 24129315
T103 Phosphorylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
S220 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S237 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S238 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S240 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S241 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S242 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S243 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S244 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S245 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S246 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S249 O-Glycosylation GlyGen 34846842
S249 Phosphorylation PhosphoSitePlus
T336 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S368 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
T385 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S419 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S427 Phosphorylation PhosphoSitePlus
S430 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K446 Ubiquitination PhosphoSitePlus
T449 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T469 Phosphorylation PhosphoSitePlus
T480 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S497 Phosphorylation PhosphoSitePlus
T499 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
S505 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S513 Phosphorylation PhosphoSitePlus
S525 Phosphorylation PhosphoSitePlus
S538 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 15302935
S541 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T542 Phosphorylation PhosphoSitePlus
S544 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
Y548 Phosphorylation PhosphoSitePlus
S558 Phosphorylation PhosphoSitePlus
S559 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S559 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163
S574 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163
T582 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S583 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163
T603 Phosphorylation PhosphoSitePlus
S609 Phosphorylation PhosphoSitePlus
S627 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
T635 Phosphorylation PhosphoSitePlus
S640 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163
S686 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
T693 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S694 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
T696 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S699 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S699 Phosphorylation PhosphoSitePlus
S701 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S701 Phosphorylation PhosphoSitePlus
S704 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S704 Phosphorylation PhosphoSitePlus
S708 Phosphorylation PhosphoSitePlus
K710 Ubiquitination PhosphoSitePlus
S807 Phosphorylation PhosphoSitePlus
S810 Phosphorylation PhosphoSitePlus
K823 Sumoylation PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus
S826 Phosphorylation PhosphoSitePlus
T827 Phosphorylation PhosphoSitePlus
T837 Phosphorylation PhosphoSitePlus
Y839 Phosphorylation PhosphoSitePlus
K844 Acetylation PhosphoSitePlus
K844 Sumoylation PhosphoSitePlus
K844 Ubiquitination PhosphoSitePlus
S852 Phosphorylation PhosphoSitePlus
S861 Phosphorylation PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
S871 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...18220336
S884 Phosphorylation PhosphoSitePlus
T903 Phosphorylation PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
K929 Sumoylation PhosphoSitePlus
K957 Acetylation PhosphoSitePlus
S966 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 18220336
S976 Phosphorylation PhosphoSitePlus
T986 Phosphorylation PhosphoSitePlus
R990 Methylation PhosphoSitePlus
R994 Methylation PhosphoSitePlus
R998 Methylation PhosphoSitePlus
S1005 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
S1007 Phosphorylation PhosphoSitePlus
Y1009 Phosphorylation PhosphoSitePlus
K1015 Acetylation PhosphoSitePlus
S1019 Phosphorylation PhosphoSitePlus
R1024 Methylation PhosphoSitePlus   UniProt 24129315
S1047 Phosphorylation PhosphoSitePlus
T1050 Phosphorylation PhosphoSitePlus
S1053 Phosphorylation PhosphoSitePlus   UniProt 20068231
T1058 Phosphorylation PhosphoSitePlus
Y1072 Phosphorylation PhosphoSitePlus
K1086 Ubiquitination PhosphoSitePlus
S1122 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S1134 Phosphorylation PhosphoSitePlus
S1196 Phosphorylation PhosphoSitePlus
S1234 Phosphorylation PhosphoSitePlus
S1259 Phosphorylation PhosphoSitePlus
S1262 Phosphorylation PhosphoSitePlus
S1266 Phosphorylation PhosphoSitePlus
K1267 Acetylation PhosphoSitePlus
K1267 Ubiquitination PhosphoSitePlus
S1270 Phosphorylation PhosphoSitePlus
T1278 O-Glycosylation GlyGen 30379171
T1278 Phosphorylation PhosphoSitePlus
K1294 Ubiquitination PhosphoSitePlus
S1305 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1322 Phosphorylation PhosphoSitePlus
T1332 Phosphorylation PhosphoSitePlus
T1334 Phosphorylation PhosphoSitePlus
S1335 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K1351 Sumoylation PhosphoSitePlus
S1361 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1367 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1370 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1372 Phosphorylation PhosphoSitePlus
T1379 Phosphorylation phospho.ELM 18669648
S1414 Phosphorylation PhosphoSitePlus
S1418 Phosphorylation PhosphoSitePlus
K1428 Acetylation PhosphoSitePlus
S1440 Phosphorylation PhosphoSitePlus
K1446 Sumoylation PhosphoSitePlus
K1446 Ubiquitination PhosphoSitePlus
K1458 Ubiquitination PhosphoSitePlus
S1474 O-Glycosylation GlyGen 34846842, 28411811, 34019948, ...27114449, 30379171, 32574038, 35254053, 33214551, 30059200, 35132862, 31492838, 35289036, 29351928, 29237092
S1482 Phosphorylation PhosphoSitePlus
T1518 Phosphorylation PhosphoSitePlus
T1520 Phosphorylation PhosphoSitePlus
S1522 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
S1536 Phosphorylation PhosphoSitePlus
K1613 Ubiquitination PhosphoSitePlus
K1615 Ubiquitination PhosphoSitePlus
Y1616 Phosphorylation PhosphoSitePlus
S1669 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T1671 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 15302935, ...18669648, 20068231
S1713 Phosphorylation PhosphoSitePlus
S1755 Phosphorylation PhosphoSitePlus
S1757 Phosphorylation PhosphoSitePlus
S1760 Phosphorylation PhosphoSitePlus
T1762 Phosphorylation PhosphoSitePlus
T1764 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1792 Phosphorylation PhosphoSitePlus
C1890 Methylation IEDB 31844290
Y1900 Phosphorylation PhosphoSitePlus
S1953 Phosphorylation PhosphoSitePlus
S1957 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S31 Phosphorylation HPRD 18669648
S419 Phosphorylation HPRD 18669648, 20068231
T421 Phosphorylation HPRD 20068231
S427 Phosphorylation HPRD 20068231
S430 Phosphorylation HPRD 18669648, 20068231
T449 Phosphorylation HPRD 18669648
T480 Phosphorylation HPRD 18669648
S505 Phosphorylation HPRD 17525332
S538 Phosphorylation HPRD 19413330, 18669648, 15302935, ...19664995
S541 Phosphorylation HPRD 18669648
S544 Phosphorylation HPRD 18669648
Y548 Phosphorylation HPRD 15592455
S558 Phosphorylation HPRD 19664995, 19691289
S559 Phosphorylation HPRD 19413330, 18669648, 15302935, ...19664995
S574 Phosphorylation HPRD 19651622, 18669648, 15302935, ...19664995, 20068231
T582 Phosphorylation HPRD 18669648, 20068231
S583 Phosphorylation HPRD 18669648, 15302935, 20068231
S627 Phosphorylation HPRD 17525332
T635 Phosphorylation HPRD 19413330
S640 Phosphorylation HPRD 19413330, 17525332
S865 Phosphorylation HPRD 18212344
S871 Phosphorylation HPRD 17322306, 18669648, 19664995, ...20068231
T903 Phosphorylation HPRD 20068231
S905 Phosphorylation HPRD 20068231
S916 Phosphorylation HPRD 20068231
S966 Phosphorylation HPRD 20068231
S1005 Phosphorylation HPRD 18669648, 17081983
S1019 Phosphorylation HPRD 18212344, 20068231
S1053 Phosphorylation HPRD 20068231
S1122 Phosphorylation HPRD 17081983
S1322 Phosphorylation HPRD 20068231
S1325 Phosphorylation HPRD 20068231
T1332 Phosphorylation HPRD 19664995, 20068231
S1335 Phosphorylation HPRD 19413330, 18669648, 19664995
S1361 Phosphorylation HPRD 18669648
S1367 Phosphorylation HPRD 18669648, 20068231
S1370 Phosphorylation HPRD 18669648, 18452278
T1379 Phosphorylation HPRD 18669648
S1522 Phosphorylation HPRD 19413330, 19651622, 18669648, ...19007248, 20068231
S1669 Phosphorylation HPRD 18669648, 20058876
T1671 Phosphorylation HPRD 15302935, 20058876, 19664995, ...19691289, 18669648, 20068231
T1764 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S31 Phosphorylation HPRD 18669648
S419 Phosphorylation HPRD 18669648, 20068231
T421 Phosphorylation HPRD 20068231
S427 Phosphorylation HPRD 20068231
S430 Phosphorylation HPRD 18669648, 20068231
T449 Phosphorylation HPRD 18669648
T480 Phosphorylation HPRD 18669648
S505 Phosphorylation HPRD 17525332
S538 Phosphorylation HPRD 19413330, 18669648, 15302935, ...19664995
S541 Phosphorylation HPRD 18669648
S544 Phosphorylation HPRD 18669648
Y548 Phosphorylation HPRD 15592455
S558 Phosphorylation HPRD 19664995, 19691289
S559 Phosphorylation HPRD 19413330, 18669648, 15302935, ...19664995
S574 Phosphorylation HPRD 19651622, 18669648, 15302935, ...19664995, 20068231
T582 Phosphorylation HPRD 18669648, 20068231
S583 Phosphorylation HPRD 18669648, 15302935, 20068231
S627 Phosphorylation HPRD 17525332
T635 Phosphorylation HPRD 19413330
S640 Phosphorylation HPRD 19413330, 17525332
S865 Phosphorylation HPRD 18212344
S871 Phosphorylation HPRD 17322306, 18669648, 19664995, ...20068231
T903 Phosphorylation HPRD 20068231
S905 Phosphorylation HPRD 20068231
S916 Phosphorylation HPRD 20068231
S966 Phosphorylation HPRD 20068231
S1005 Phosphorylation HPRD 18669648, 17081983
S1019 Phosphorylation HPRD 18212344, 20068231
S1053 Phosphorylation HPRD 20068231
S1122 Phosphorylation HPRD 17081983
S1322 Phosphorylation HPRD 20068231
S1325 Phosphorylation HPRD 20068231
T1332 Phosphorylation HPRD 19664995, 20068231
S1335 Phosphorylation HPRD 19413330, 18669648, 19664995
S1361 Phosphorylation HPRD 18669648
S1367 Phosphorylation HPRD 18669648, 20068231
S1370 Phosphorylation HPRD 18669648, 18452278
T1379 Phosphorylation HPRD 18669648
S1522 Phosphorylation HPRD 19413330, 19651622, 18669648, ...19007248, 20068231
S1669 Phosphorylation HPRD 18669648, 20058876
T1671 Phosphorylation HPRD 15302935, 20058876, 19664995, ...19691289, 18669648, 20068231
T1764 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S220 F220 Biomuta DOID:4159 / skin cancer [ cosmic ]
S237 C237 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S238 C238 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S240 F240 Biomuta DOID:4159 / skin cancer [ cosmic ]
S242 F242 Biomuta DOID:4159 / skin cancer [ cosmic ]
S245 F245 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S501 P501 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
S574 N574 Biomuta DOID:363 / uterine cancer [ icgc ]
S609 C609 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T693 M693 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S694 G694 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S699 N699 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S701 F701 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S807 I807 Biomuta DOID:363 / uterine cancer [ icgc ]
S825 R825 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S825 G825 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S826 N826 Biomuta DOID:363 / uterine cancer [ icgc ]
K844 E844 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S865 L865 Biomuta DOID:4159 / skin cancer [ cosmic ]
S871 C871 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K957 N957 Biomuta DOID:363 / uterine cancer [ icgc ]
R994 T994 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R1024 K1024 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
K1086 N1086 Biomuta DOID:1319 / brain cancer [ cosmic ]
T1278 I1278 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S1335 N1335 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1361 F1361 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1474 N1474 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T1520 P1520 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T1520 M1520 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S1522 T1522 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S1522 L1522 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S1760 A1760 Biomuta DOID:3571 / liver cancer [ cosmic ]
S1953 C1953 Biomuta DOID:1324 / lung cancer [ cosmic ]