iPTMnet Report for Q9UGM6 (WARS2)
Protein Information
UniProt AC / UniProt ID | Q9UGM6 / SYWM_HUMAN |
Protein Name | Tryptophan--tRNA ligase, mitochondrial precursor |
Gene Name | Name: WARS2 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UGM6 |
PRO Name | tryptophan--tRNA ligase, mitochondrial (human) |
Definition | A tryptophan--tRNA ligase, mitochondrial that is encoded in the genome of human. |
Short Label | hWARS2 |
Category | organism-gene |
Q9UGM6 (WARS2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S5 | Phosphorylation | score1 | PhosphoSitePlus | |||
S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y200 | Phosphorylation | score1 | PhosphoSitePlus | |||
S209 | Phosphorylation | score1 | PhosphoSitePlus | |||
T212 | Phosphorylation | score1 | PhosphoSitePlus | |||
S213 | Phosphorylation | score1 | PhosphoSitePlus | |||
S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
S230 | O-Glycosylation | score1 | GlyGen | 30379171, 28510447 | ||
T241 | Phosphorylation | score1 | PhosphoSitePlus | |||
T299 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y302 | Phosphorylation | score1 | PhosphoSitePlus | |||
K341 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S5 | L5 | Biomuta | DOID:4362 / cervical cancer [ cosmic, icgc ] | |
S224 | F224 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |