iPTMnet Report for Q9UF56 (FBXL17)
Protein Information
| UniProt AC / UniProt ID | Q9UF56 / FXL17_HUMAN |
| Protein Name | F-box/LRR-repeat protein 17 |
| Gene Name | Name: FBXL17 Synonyms:FBL17; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UF56 |
| PRO Name | F-box/LRR-repeat protein 17 (human) |
| Definition | An F-box/LRR-repeat protein 17 that is encoded in the genome of human. |
| Short Label | hFBXL17 |
| Category | organism-gene |
DAG ViewQ9UF56 (FBXL17) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S139 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T183 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T208 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K380 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S383 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S429 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C437 | Methylation | score1 | IEDB | 31844290 | ||
| K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K457 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S461 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K467 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K487 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K501 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C515 | Methylation | score1 | IEDB | 31844290 | ||
| T557 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K595 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K643 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y688 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q9UMX1 (SUFU) | S352 | Q9UF56 (FBXL17) | decreased_association | eFIP | 27234298 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S383 | P383 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] |
