iPTMnet Report for Q9UBW5 (BIN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UBW5 / BIN2_HUMAN
Protein Name Bridging integrator 2
Gene Name Name: BIN2
Synonyms:BRAP1;
Organism Homo sapiens (Human)

PRO ID PR:Q9UBW5
DAG View
PRO Name bridging integrator 2 (human)
Definition A bridging integrator 2 that is encoded in the genome of human.
Short Label hBIN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UBW5 (BIN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Acetylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
K20 Acetylation PhosphoSitePlus
K27 Acetylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
T124 Phosphorylation PhosphoSitePlus
K145 Acetylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
Y149 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K164 Acetylation PhosphoSitePlus
K165 Acetylation PhosphoSitePlus
K169 Acetylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
S236 Phosphorylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
S263 Phosphorylation PhosphoSitePlus
T268 Phosphorylation PhosphoSitePlus
T270 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S273 Phosphorylation PhosphoSitePlus   UniProt 19690332
T276 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
S310 Phosphorylation PhosphoSitePlus
S349 Phosphorylation PhosphoSitePlus
T352 Phosphorylation PhosphoSitePlus
S357 Phosphorylation PhosphoSitePlus   UniProt 19690332
T366 Phosphorylation PhosphoSitePlus
S369 Phosphorylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
T385 Phosphorylation PhosphoSitePlus
T393 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus   UniProt 24275569
S398 Phosphorylation PhosphoSitePlus
S406 Phosphorylation PhosphoSitePlus
T410 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
S415 Phosphorylation PhosphoSitePlus
T423 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S429 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
S435 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus   UniProt 19690332
T438 Phosphorylation PhosphoSitePlus   UniProt 19690332
S440 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus   UniProt 19690332, 24275569
T446 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus   UniProt 19690332
S451 Phosphorylation PhosphoSitePlus   UniProt 24275569
T454 Phosphorylation PhosphoSitePlus
T456 Phosphorylation PhosphoSitePlus
S458 Phosphorylation PhosphoSitePlus   UniProt 19690332
T461 Phosphorylation PhosphoSitePlus
S462 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
T478 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S285 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S415 Y415 Biomuta DOID:184 / bone cancer [ cosmic ]
S430 T430 Biomuta DOID:3571 / liver cancer [ cosmic ]