iPTMnet Report for Q9UBR4 (LHX3)
Protein Information
UniProt AC / UniProt ID | Q9UBR4 / LHX3_HUMAN |
Protein Name | LIM/homeobox protein Lhx3 |
Gene Name | Name: LHX3 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UBR4 |
PRO Name | LIM/homeobox protein Lhx3 (human) |
Definition | A LIM/homeobox protein Lhx3 that is encoded in the genome of human. |
Short Label | hLHX3 |
Category | organism-gene |
Q9UBR4 (LHX3) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T63 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 15517599 | ||
S71 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P UniProt | 15517599 | ||
R159 | Methylation | score1 | PhosphoSitePlus | |||
R161 | Methylation | score1 | PhosphoSitePlus | |||
S174 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y176 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y227 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 15517599 | ||
S234 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 15517599 | ||
S238 | Phosphorylation | score3 | PhosphoSitePlus UniProt | 15517599 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R159 | W159 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
R161 | C161 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
R161 | H161 | Biomuta | DOID:5041 / esophageal cancer [ cosmic ] | |
S174 | R174 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
Y176 | * | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] |