iPTMnet Report for Q9UBQ7 (GRHPR)
Protein Information
| UniProt AC / UniProt ID | Q9UBQ7 / GRHPR_HUMAN |
| Protein Name | Glyoxylate reductase/hydroxypyruvate reductase |
| Gene Name | Name: GRHPR Synonyms:GLXR;ORFNames:MSTP035; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9UBQ7 |
| PRO Name | glyoxylate reductase/hydroxypyruvate reductase (human) |
| Definition | A glyoxylate reductase/hydroxypyruvate reductase that is encoded in the genome of human. |
| Short Label | hGRHPR |
| Category | organism-gene |
DAG ViewQ9UBQ7 (GRHPR) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K8 | Acetylation | score1 | IEDB | 34357683 | ||
| C29 | Methylation | score1 | IEDB | 31844290 | ||
| C29 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| S36 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K65 | Acetylation | score1 | PhosphoSitePlus | |||
| K65 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T80 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K94 | Acetylation | score1 | PhosphoSitePlus | |||
| K94 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T122 | O-Glycosylation | score1 | GlyGen | 36240223, 34019948, 34229054 | ||
| K173 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K233 | Acetylation | score1 | PhosphoSitePlus | |||
| K235 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T237 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y255 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K262 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T271 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S272 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| T298 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 24275569 | ||
| T304 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S306 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K327 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C29 | F29 | Biomuta | [ cosmic ] DOID:1115 / sarcoma [ icgc ] | |
| S36 | L36 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S36 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K43 | Q43 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| K233 | T233 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T237 | R237 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| T271 | M271 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |
