iPTMnet Report for Q9UBI6 (GNG12)
Protein Information
UniProt AC / UniProt ID | Q9UBI6 / GBG12_HUMAN |
Protein Name | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 precursor |
Gene Name | Name: GNG12 |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9UBI6 |
PRO Name | guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (human) |
Definition | A guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 that is encoded in the genome of human. |
Short Label | hGNG12 |
Category | organism-gene |
Q9UBI6 (GNG12) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Acetylation | score1 | UniProt | 22814378 | ||
S2 | Phosphorylation | score4 | HPRD PhosphoSitePlus | 20068231, 7493986 | ||
K4 | Ubiquitination | score1 | PhosphoSitePlus | |||
T5 | Phosphorylation | score1 | PhosphoSitePlus | |||
S7 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
T8 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 20068231 | ||
S26 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18669648, 17081983, 20068231 | ||
K34 | Ubiquitination | score1 | PhosphoSitePlus | |||
S41 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18669648, 20068231 | ||
Y42 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17081983 | ||
C43 | S-Nitrosylation | score0 | dbSNO | 2212679 | ||
S49 | Phosphorylation | score2 | HPRD PhosphoSitePlus UniProt | 18669648, 24275569 | ||
K64 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S2 | F2 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
S7 | T7 | Biomuta | DOID:10283 / prostate cancer [ cosmic ] | |
S7 | I7 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
K34 | N34 | Biomuta | DOID:9256 / colorectal cancer [ icgc ] |