Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9UBH6 / S53A1_HUMAN
Protein Name Solute carrier family 53 member 1
Gene Name Name: XPR1
Synonyms:SLC53A1;
Organism Homo sapiens (Human)

PRO ID PR:Q9UBH6
DAG View
PRO Name xenotropic and polytropic retrovirus receptor 1 (human)
Definition A xenotropic and polytropic retrovirus receptor 1 that is encoded in the genome of human.
Short Label hXPR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9UBH6 (XPR1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K48 Ubiquitination PhosphoSitePlus
Y50 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K64 Ubiquitination PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
T105 Phosphorylation PhosphoSitePlus
T106 Phosphorylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
R273 Methylation PhosphoSitePlus
Y483 Phosphorylation PhosphoSitePlus
T498 Phosphorylation PhosphoSitePlus
T574 Phosphorylation PhosphoSitePlus
T594 Phosphorylation PhosphoSitePlus
S660 Phosphorylation IEDB   PhosphoSitePlus 35494241
K662 Ubiquitination PhosphoSitePlus
Y663 Phosphorylation PhosphoSitePlus
S666 Phosphorylation PhosphoSitePlus
S668 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S676 Phosphorylation PhosphoSitePlus
S678 Phosphorylation PhosphoSitePlus
K684 Ubiquitination PhosphoSitePlus
T690 Phosphorylation PhosphoSitePlus   UniProt 18669648, 17081983, 20068231
Site PTM Type PTM Enzyme Score Source PMID
Y50 Phosphorylation HPRD 18212344
S666 Phosphorylation HPRD 18767875, 18578522, 17081983
S668 Phosphorylation HPRD 18767875, 18669648, 17081983
T690 Phosphorylation HPRD 19413330, 18578522, 17081983, ...18767875, 19651622, 18669648, 19415658, 20068231
T696 Phosphorylation HPRD 19651622


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K64 N64 Biomuta DOID:263 / kidney cancer [ cosmic ]
R273 W273 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:4362 / cervical cancer [ icgc ] DOID:5041 / esophageal cancer [ cosmic ]
S666 I666 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:8618 / oral cavity cancer [ cosmic ]
S668 C668 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S668 F668 Biomuta DOID:4159 / skin cancer [ cosmic ]