iPTMnet Report for Q9P2S2 (NRXN2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9P2S2 / NRX2A_HUMAN
Protein Name Neurexin-2 precursor
Gene Name Name: NRXN2
Synonyms:KIAA0921;
Organism Homo sapiens (Human)

PRO ID PR:Q9P2S2
DAG View
PRO Name neurexin-2-alpha (human)
Definition A neurexin-2-alpha that is encoded in the genome of human.
Short Label hNRXN2-alpha
Category organism-seqgroup

Interactive Sequence View

Select/align proteoforms across species


Q9P2S2 (NRXN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T330 Phosphorylation PhosphoSitePlus
S544 Phosphorylation PhosphoSitePlus
S546 Phosphorylation PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
S571 Phosphorylation PhosphoSitePlus
S580 Phosphorylation PhosphoSitePlus
S601 Phosphorylation PhosphoSitePlus
S757 Phosphorylation PhosphoSitePlus
S762 Phosphorylation PhosphoSitePlus
Y766 Phosphorylation PhosphoSitePlus
T772 Phosphorylation PhosphoSitePlus
S774 Phosphorylation PhosphoSitePlus
S777 Phosphorylation PhosphoSitePlus
T780 Phosphorylation PhosphoSitePlus
S992 Phosphorylation PhosphoSitePlus
Y1269 Phosphorylation PhosphoSitePlus
T1364 Phosphorylation PhosphoSitePlus
T1368 Phosphorylation PhosphoSitePlus
S1382 Phosphorylation PhosphoSitePlus
S1528 Phosphorylation PhosphoSitePlus
S1554 O-Glycosylation GlyGen 30459171
Y1676 Phosphorylation PhosphoSitePlus
Y1710 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S546 N546 Biomuta DOID:4159 / skin cancer [ cosmic ]
S547 F547 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S601 F601 Biomuta DOID:4159 / skin cancer [ cosmic ]
S757 Y757 Biomuta DOID:3953 / adrenal gland cancer [ cosmic ]
S762 F762 Biomuta [ cosmic ]
S762 Y762 Biomuta DOID:1324 / lung cancer [ cosmic ]
S774 F774 Biomuta DOID:4159 / skin cancer [ cosmic ]
T780 I780 Biomuta [ cosmic ]
T1364 N1364 Biomuta DOID:1324 / lung cancer [ cosmic ]