iPTMnet Report for Q9NZN3 (EHD3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZN3 / EHD3_HUMAN
Protein Name EH domain-containing protein 3
Gene Name Name: EHD3
Synonyms:EHD2;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZN3
DAG View
PRO Name EH domain-containing protein 3 (human)
Definition An EH domain-containing protein 3 that is encoded in the genome of human.
Short Label hEHD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZN3 (EHD3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 12665801
K32 Methylation PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
T69 Phosphorylation PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K205 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
T226 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K315 Sumoylation PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
Y339 Phosphorylation PhosphoSitePlus
Y453 Phosphorylation PhosphoSitePlus
S456 Phosphorylation PhosphoSitePlus
T463 Phosphorylation PhosphoSitePlus
K475 Ubiquitination PhosphoSitePlus
S479 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K511 Sumoylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S456 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y40 * Biomuta DOID:363 / uterine cancer [ cosmic ]
K220 T220 Biomuta DOID:1324 / lung cancer [ cosmic ]
T226 K226 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T226 M226 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K511 T511 Biomuta DOID:4159 / skin cancer [ cosmic ]