iPTMnet Report for Q9NZ45 (CISD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NZ45 / CISD1_HUMAN
Protein Name CDGSH iron-sulfur domain-containing protein 1
Gene Name Name: CISD1
Synonyms:C10orf70,ZCD1;ORFNames:MDS029;
Organism Homo sapiens (Human)

PRO ID PR:Q9NZ45
DAG View
PRO Name CDGSH iron-sulfur domain-containing protein 1 (human)
Definition A CDGSH iron-sulfur domain-containing protein 1 that is encoded in the genome of human.
Short Label hCISD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NZ45 (CISD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
S2 Phosphorylation PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus   UniProt 25621951
K51 Acetylation PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K55 Acetylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus   UniProt 25621951
K68 Acetylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus   UniProt 25621951
Y71 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
K78 Ubiquitination UniProt 25621951
K79 Acetylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus   UniProt 25621951
K89 Ubiquitination UniProt 25621951
K104 Acetylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus   UniProt 25621951
K105 Ubiquitination UniProt 25621951
K106 Ubiquitination UniProt 25621951


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S7 Y7 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K78 * Biomuta DOID:3571 / liver cancer [ cosmic ]
K105 E105 Biomuta DOID:363 / uterine cancer [ icgc ]