iPTMnet Report for Q9NYV6 (RRN3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYV6 / RRN3_HUMAN
Protein Name RNA polymerase I-specific transcription initiation factor RRN3
Gene Name Name: RRN3
Synonyms:TIFIA;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYV6
DAG View
PRO Name RNA polymerase I-specific transcription initiation factor RRN3 (human)
Definition An RNA polymerase I-specific transcription initiation factor RRN3 that is encoded in the genome of human.
Short Label hRRN3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYV6 (RRN3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R9 Methylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus
K22 Ubiquitination PhosphoSitePlus
S44 Phosphorylation P24941 (CDK2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 18669648, 15004009, 29873780
K62 Ubiquitination PhosphoSitePlus
K65 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
S170 Phosphorylation P68400 (CSNK2A1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18669648, 18559419, 27257073
S172 Phosphorylation P68400 (CSNK2A1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18669648, 18559419, 27257073
S199 Phosphorylation PhosphoSitePlus
T200 Phosphorylation P45984 (MAPK9) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15805466
C224 Methylation IEDB 31844290
S233 Phosphorylation PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
T271 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
C329 Methylation IEDB 31844290
K334 Ubiquitination PhosphoSitePlus
C362 Methylation IEDB 31844290
K415 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
C525 Methylation IEDB 31844290
C565 Methylation IEDB 31844290
K568 Ubiquitination PhosphoSitePlus
K593 Ubiquitination PhosphoSitePlus
K598 Ubiquitination PhosphoSitePlus
K610 Ubiquitination PhosphoSitePlus
T623 Phosphorylation PhosphoSitePlus
S633 Phosphorylation P27361 (MAPK3) phospho.ELM   PhosphoSitePlus   Signor 12620228
S635 Phosphorylation Q13131 (PRKAA1) PhosphoSitePlus   Signor 19815529
S636 Phosphorylation PhosphoSitePlus
S640 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S649 Phosphorylation P51812 (RPS6KA3) , P27361 (MAPK3) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 12620228, 29873780, 15558034
Site PTM Type PTM Enzyme Score Source PMID
S44 Phosphorylation HPRD 18691976, 18669648, 15004009, ...19664994, 19664995
S170 Phosphorylation HPRD 18669648, 20068231, 18452278
S172 Phosphorylation HPRD 18669648, 20068231, 18452278
S199 Phosphorylation HPRD 15004009
S640 Phosphorylation HPRD 18669648


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q9NYV6 (RRN3) S172 Q9UNA4 (POLI) unknown eFIP 18559419
Phosphorylation Q9NYV6 (RRN3) T200 Q9UNA4 (POLI) inhibited_association eFIP 15805466
Phosphorylation Q9NYV6 (RRN3) S649 Q9UNA4 (POLI) unknown eFIP 15558034
Phosphorylation Q9NYV6 (RRN3) S172 Q9UNA4 (POLI) unknown eFIP 27257073