iPTMnet Report for Q9NYF3 (FAM53C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NYF3 / FA53C_HUMAN
Protein Name Protein FAM53C
Gene Name Name: FAM53C
Synonyms:C5orf6;
Organism Homo sapiens (Human)

PRO ID PR:Q9NYF3
DAG View
PRO Name protein FAM53C (human)
Definition A protein FAM53C that is encoded in the genome of human.
Short Label hFAM53C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NYF3 (FAM53C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22223895
T6 Phosphorylation PhosphoSitePlus
T13 Phosphorylation PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
S122 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 20058876, 19664994, 15302935, ...18669648, 23186163, 20068231
S128 O-Glycosylation GlyGen 30379171, 34019948
T143 Phosphorylation PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus   UniProt 23186163
S190 Phosphorylation IEDB   PhosphoSitePlus 33936100, 27869121
S232 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 17081983, ...19651622, 18669648, 20068231
S234 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 17081983, ...18220336, 18767875, 19664994, 19651622, 18669648, 19690332, 20068231
S236 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648
S242 Phosphorylation HPRD   PhosphoSitePlus 17081983
S247 Phosphorylation PhosphoSitePlus
S250 Phosphorylation HPRD   PhosphoSitePlus 19651622
S251 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648
S254 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 19651622, 18669648
S255 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 23186163
S271 Phosphorylation PhosphoSitePlus
S273 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S299 Phosphorylation PhosphoSitePlus   UniProt 23186163
S311 Phosphorylation PhosphoSitePlus
C315 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T13 I13 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S122 L122 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T143 A143 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S232 F232 Biomuta DOID:4159 / skin cancer [ cosmic ]
S254 F254 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S273 L273 Biomuta DOID:4159 / skin cancer [ cosmic ]
C315 F315 Biomuta DOID:4606 / bile duct cancer [ cosmic ]