iPTMnet Report for Q9NYA4 (MTMR4)
Protein Information
UniProt AC / UniProt ID | Q9NYA4 / MTMR4_HUMAN |
Protein Name | Myotubularin-related protein 4 |
Gene Name | Name: MTMR4 Synonyms:KIAA0647,ZFYVE11; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NYA4 |
PRO Name | myotubularin-related protein 4 (human) |
Definition | A myotubularin-related protein 4 that is encoded in the genome of human. |
Short Label | hMTMR4 |
Category | organism-gene |
Q9NYA4 (MTMR4) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S8 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K92 | Methylation | score1 | PhosphoSitePlus | |||
K95 | Methylation | score1 | PhosphoSitePlus | |||
K184 | Ubiquitination | score1 | PhosphoSitePlus | |||
K192 | Ubiquitination | score1 | PhosphoSitePlus | |||
T200 | O-Glycosylation | score1 | GlyGen | 29351928 | ||
K202 | Ubiquitination | score1 | PhosphoSitePlus | |||
K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
C486 | Methylation | score1 | IEDB | 31844290 | ||
C577 | Methylation | score1 | IEDB | 31844290 | ||
S601 | Phosphorylation | score1 | PhosphoSitePlus | |||
T608 | Phosphorylation | score1 | PhosphoSitePlus | |||
S610 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
T625 | Phosphorylation | score1 | PhosphoSitePlus | |||
S628 | Phosphorylation | score1 | PhosphoSitePlus | |||
S629 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S718 | Phosphorylation | score1 | PhosphoSitePlus | |||
K729 | Ubiquitination | score1 | PhosphoSitePlus | |||
K882 | Ubiquitination | score1 | PhosphoSitePlus | |||
S961 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1002 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1081 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1086 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S8 | N8 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K192 | E192 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
C486 | F486 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
C577 | Y577 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S601 | P601 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T625 | I625 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
T625 | A625 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S718 | T718 | Biomuta | DOID:1319 / brain cancer [ cosmic, icgc ] | |
S961 | * | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
S961 | L961 | Biomuta | DOID:4362 / cervical cancer [ icgc ] |