Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NXS3 / KLH28_HUMAN
Protein Name Kelch-like protein 28
Gene Name Name: KLHL28
Synonyms:BTBD5;
Organism Homo sapiens (Human)

PRO ID PR:Q9NXS3
DAG View
PRO Name kelch-like protein 28 (human)
Definition A kelch-like protein 28 that is encoded in the genome of human.
Short Label hKLHL28
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NXS3 (KLHL28) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C35 Methylation IEDB 31844290
Y216 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
K232 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
Y334 Phosphorylation PhosphoSitePlus
K351 Ubiquitination PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
Y406 Phosphorylation PhosphoSitePlus
K412 Ubiquitination PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y216 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y334 C334 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y389 D389 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]