iPTMnet Report for Q9NXG2 (THUMPD1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NXG2 / THUM1_HUMAN
Protein Name THUMP domain-containing protein 1
Gene Name Name: THUMPD1
Organism Homo sapiens (Human)

PRO ID PR:Q9NXG2
DAG View
PRO Name THUMP domain-containing protein 1 (human)
Definition A THUMP domain-containing protein 1 that is encoded in the genome of human.
Short Label hTHUMPD1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NXG2 (THUMPD1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
T8 O-Glycosylation GlyGen 23301498, 34019948, 28510447, ...29351928
T9 O-Glycosylation GlyGen 23301498, 34019948, 28510447, ...29351928
K15 Acetylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
K26 Acetylation PhosphoSitePlus
K26 Methylation PhosphoSitePlus
T49 Phosphorylation PhosphoSitePlus
T79 Phosphorylation PhosphoSitePlus   UniProt 24275569
S86 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 17287340, 17081983, ...20230923, 18767875, 19664994, 18452278, 19651622, 18669648, 19690332, 24275569, 18707149, 20166139, 23186163, 19415658, 20068231
S88 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 17081983, ...20230923, 18767875, 19664994, 18452278, 19651622, 17322306, 18669648, 19415658, 24275569, 18707149, 20166139, 17287340, 19690332, 20068231
S119 Phosphorylation PhosphoSitePlus   UniProt 23186163
K178 Ubiquitination PhosphoSitePlus
Y179 Phosphorylation PhosphoSitePlus
T182 Phosphorylation PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
C222 Methylation IEDB 31844290
K254 Ubiquitination PhosphoSitePlus
K261 Acetylation PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus   UniProt 23186163
K272 Ubiquitination PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
K285 Acetylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus
S345 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T49 N49 Biomuta DOID:363 / uterine cancer [ icgc ]
S88 I88 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y262 F262 Biomuta DOID:3571 / liver cancer [ cosmic ]