Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NWC5 / TM45A_HUMAN
Protein Name Transmembrane protein 45A
Gene Name Name: TMEM45A
Synonyms:DERP7,DNAPTP4;
Organism Homo sapiens (Human)

PRO ID PR:Q9NWC5
DAG View
PRO Name transmembrane protein 45A (human)
Definition A transmembrane protein 45A that is encoded in the genome of human.
Short Label hTMEM45A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NWC5 (TMEM45A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K43 Ubiquitination PhosphoSitePlus
S256 Phosphorylation HPRD   PhosphoSitePlus 18767875
S257 Phosphorylation PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S256 F256 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K263 N263 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S271 * Biomuta DOID:263 / kidney cancer [ cosmic ]