iPTMnet Report for Q9NWC5 (TMEM45A)
Protein Information
UniProt AC / UniProt ID | Q9NWC5 / TM45A_HUMAN |
Protein Name | Transmembrane protein 45A |
Gene Name | Name: TMEM45A Synonyms:DERP7,DNAPTP4; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NWC5 |
PRO Name | transmembrane protein 45A (human) |
Definition | A transmembrane protein 45A that is encoded in the genome of human. |
Short Label | hTMEM45A |
Category | organism-gene |
Q9NWC5 (TMEM45A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K43 | Ubiquitination | score1 | PhosphoSitePlus | |||
S256 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 18767875 | ||
S257 | Phosphorylation | score1 | PhosphoSitePlus | |||
K263 | Ubiquitination | score1 | PhosphoSitePlus | |||
S271 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S256 | F256 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K263 | N263 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S271 | * | Biomuta | DOID:263 / kidney cancer [ cosmic ] |