iPTMnet Report for Q9NVX2 (NLE1)
Protein Information
UniProt AC / UniProt ID | Q9NVX2 / NLE1_HUMAN |
Protein Name | Notchless protein homolog 1 |
Gene Name | Name: NLE1 ORFNames:HUSSY-07; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NVX2 |
PRO Name | notchless protein homolog 1 (human) |
Definition | A notchless protein homolog 1 that is encoded in the genome of human. |
Short Label | hNLE1 |
Category | organism-gene |
Q9NVX2 (NLE1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895 | ||
T40 | Phosphorylation | score1 | PhosphoSitePlus | |||
S79 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332 | ||
Y128 | Phosphorylation | score1 | PhosphoSitePlus | |||
K176 | Ubiquitination | score1 | PhosphoSitePlus | |||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
K224 | Ubiquitination | score1 | PhosphoSitePlus | |||
K326 | Ubiquitination | score1 | PhosphoSitePlus | |||
K439 | Ubiquitination | score1 | PhosphoSitePlus | |||
K444 | Ubiquitination | score1 | PhosphoSitePlus | |||
K447 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T40 | Phosphorylation | score0 | HPRD | 20068231 | ||
S79 | Phosphorylation | score0 | HPRD | 17525332 | ||
Y128 | Phosphorylation | score0 | HPRD | 20068231 | ||
S131 | Phosphorylation | score0 | HPRD | 20068231 | ||
S133 | Phosphorylation | score0 | HPRD | 20068231 | ||
T136 | Phosphorylation | score0 | HPRD | 20068231 | ||
T137 | Phosphorylation | score0 | HPRD | 20068231 | ||
T246 | Phosphorylation | score0 | HPRD | 20068231 | ||
S381 | Phosphorylation | score0 | HPRD | 20068231 | ||
S384 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K176 | M176 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K224 | R224 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
K439 | N439 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |