iPTMnet Report for Q9NVW2 (RLIM)
Protein Information
UniProt AC / UniProt ID | Q9NVW2 / RNF12_HUMAN |
Protein Name | E3 ubiquitin-protein ligase RLIM |
Gene Name | Name: RLIM Synonyms:RNF12; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NVW2 |
PRO Name | E3 ubiquitin-protein ligase RLIM (human) |
Definition | An E3 ubiquitin-protein ligase RLIM that is encoded in the genome of human. |
Short Label | hRLIM |
Category | organism-gene |
Q9NVW2 (RLIM) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
M1 | Acetylation | score1 | UniProt | 22814378 | ||
K9 | Ubiquitination | score1 | PhosphoSitePlus | |||
S21 | Phosphorylation | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
R117 | Methylation | score1 | PhosphoSitePlus | |||
S132 | Phosphorylation | score1 | PhosphoSitePlus | |||
S164 | Phosphorylation | score1 | PhosphoSitePlus | |||
S181 | Phosphorylation | score1 | PhosphoSitePlus | |||
T184 | Phosphorylation | score1 | PhosphoSitePlus | |||
S185 | Phosphorylation | score1 | PhosphoSitePlus | |||
S191 | Phosphorylation | score1 | PhosphoSitePlus | |||
S195 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T196 | Phosphorylation | score1 | PhosphoSitePlus | |||
S215 | Phosphorylation | score1 | PhosphoSitePlus | |||
S228 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S230 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S236 | Phosphorylation | score1 | PhosphoSitePlus | |||
S276 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
S295 | Phosphorylation | score1 | PhosphoSitePlus | |||
S347 | Phosphorylation | score1 | PhosphoSitePlus | |||
T349 | Phosphorylation | score1 | PhosphoSitePlus | |||
T353 | Phosphorylation | score1 | PhosphoSitePlus | |||
R360 | Methylation | score1 | PhosphoSitePlus | |||
R364 | Methylation | score1 | PhosphoSitePlus | |||
S459 | Phosphorylation | score1 | PhosphoSitePlus | |||
S460 | Phosphorylation | score1 | PhosphoSitePlus | |||
S461 | Phosphorylation | score1 | PhosphoSitePlus | |||
S462 | Phosphorylation | score1 | PhosphoSitePlus | |||
S463 | Phosphorylation | score1 | PhosphoSitePlus | |||
S468 | Phosphorylation | score1 | PhosphoSitePlus | |||
S469 | Phosphorylation | score1 | PhosphoSitePlus | |||
S470 | Phosphorylation | score1 | PhosphoSitePlus | |||
S471 | Phosphorylation | score1 | PhosphoSitePlus | |||
S503 | Phosphorylation | score1 | PhosphoSitePlus | |||
S505 | Phosphorylation | score1 | PhosphoSitePlus | |||
S506 | Phosphorylation | score1 | PhosphoSitePlus | |||
K550 | Ubiquitination | score1 | PhosphoSitePlus | |||
K568 | Ubiquitination | score1 | PhosphoSitePlus | |||
K582 | Ubiquitination | score1 | PhosphoSitePlus | |||
K585 | Ubiquitination | score1 | PhosphoSitePlus | |||
C588 | Methylation | score1 | IEDB | 31844290 | ||
C596 | Methylation | score1 | IEDB | 31844290 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
R117 | K117 | Biomuta | DOID:1612 / breast cancer [ icgc ] | |
R117 | I117 | Biomuta | DOID:2394 / ovarian cancer [ cosmic ] | |
S276 | A276 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
T349 | K349 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
T353 | I353 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
R360 | Q360 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S459 | L459 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S470 | R470 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S471 | P471 | Biomuta | [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:11615 / penile cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ] | |
C588 | * | Biomuta | DOID:263 / kidney cancer [ cosmic ] |