iPTMnet Report for Q9NVV0 (TMEM38B)
Protein Information
UniProt AC / UniProt ID | Q9NVV0 / TM38B_HUMAN |
Protein Name | Trimeric intracellular cation channel type B |
Gene Name | Name: TMEM38B Synonyms:C9orf87; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NVV0 |
PRO Name | trimeric intracellular cation channel type B (human) |
Definition | A trimeric intracellular cation channel type B that is encoded in the genome of human. |
Short Label | hTMEM38B |
Category | organism-gene |
Q9NVV0 (TMEM38B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K166 | Ubiquitination | score1 | PhosphoSitePlus | |||
K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
T186 | Phosphorylation | score1 | PhosphoSitePlus | |||
S190 | Phosphorylation | score1 | PhosphoSitePlus | |||
S258 | Phosphorylation | score1 | PhosphoSitePlus | |||
S262 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18691976, 18669648, 20068231 | ||
S264 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 18691976, 18669648 | ||
S269 | Phosphorylation | score2 | HPRD phospho.ELM | 18669648 | ||
K273 | Ubiquitination | score1 | PhosphoSitePlus | |||
S279 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 19007248 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T186 | I186 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S190 | T190 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S258 | R258 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
S258 | I258 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
S269 | L269 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S279 | L279 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S279 | T279 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |