iPTMnet Report for Q9NVI1 (FANCI)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NVI1 / FANCI_HUMAN
Protein Name Fanconi anemia group I protein
Gene Name Name: FANCI
Synonyms:KIAA1794;
Organism Homo sapiens (Human)

PRO ID PR:Q9NVI1
DAG View
PRO Name Fanconi anemia group I protein (human)
Definition A Fanconi anemia group I protein that is encoded in the genome of human.
Short Label hFANCI
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NVI1 (FANCI) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Ubiquitination PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
K16 Acetylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K41 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
T62 Phosphorylation PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
Y215 Phosphorylation PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus
K331 Ubiquitination PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K339 Ubiquitination PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
T406 Phosphorylation PhosphoSitePlus
S407 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16964243
S409 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
C419 Methylation IEDB 31844290
K420 Ubiquitination PhosphoSitePlus
K431 Ubiquitination PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
C516 Methylation IEDB 31844290
K523 Ubiquitination PhosphoSitePlus   UniProt 17412408, 19589784, 17460694
S556 Phosphorylation Q13315 (ATM) PRO   PhosphoSitePlus   RLIMS-P 17478428, 31240132
S559 Phosphorylation Q13315 (ATM) PRO   PhosphoSitePlus   RLIMS-P 17478428, 31240132
S565 Phosphorylation PRO   PhosphoSitePlus
Y606 Phosphorylation PhosphoSitePlus
Y610 Phosphorylation PhosphoSitePlus
S617 Phosphorylation PRO
K638 Ubiquitination PhosphoSitePlus
K646 Acetylation PhosphoSitePlus
T653 Phosphorylation PhosphoSitePlus
K715 Ubiquitination PhosphoSitePlus
K725 Ubiquitination PhosphoSitePlus
S726 Phosphorylation PhosphoSitePlus
S730 Phosphorylation Q13315 (ATM) phospho.ELM   PhosphoSitePlus   Signor   UniProt 17478428, 17525332, 17412408
S732 Phosphorylation PhosphoSitePlus
K780 Ubiquitination PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
K799 Ubiquitination PhosphoSitePlus
T800 Phosphorylation PhosphoSitePlus
K849 Ubiquitination PhosphoSitePlus
K854 Ubiquitination PhosphoSitePlus
K869 Ubiquitination PhosphoSitePlus
K897 Ubiquitination PhosphoSitePlus
K902 Ubiquitination PhosphoSitePlus
S903 Phosphorylation PhosphoSitePlus
K926 Ubiquitination PhosphoSitePlus
K939 Ubiquitination PhosphoSitePlus
T952 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 17412408
S972 Phosphorylation Q13315 (ATM) PhosphoSitePlus 17478428
S1000 Phosphorylation PhosphoSitePlus
K1015 Ubiquitination PhosphoSitePlus
S1027 Phosphorylation PhosphoSitePlus
K1040 Ubiquitination PhosphoSitePlus
K1068 Ubiquitination PhosphoSitePlus
C1085 Methylation IEDB 31844290
K1105 Ubiquitination PhosphoSitePlus
K1107 Ubiquitination PhosphoSitePlus
S1120 Phosphorylation PhosphoSitePlus
S1121 Phosphorylation Q13315 (ATM) phospho.ELM   PhosphoSitePlus   UniProt 17478428, 17525332, 17412408
K1196 Ubiquitination PhosphoSitePlus
K1199 Ubiquitination PhosphoSitePlus
C1209 Methylation IEDB 31844290
K1221 Ubiquitination PhosphoSitePlus
K1229 Ubiquitination PhosphoSitePlus
K1232 Ubiquitination PhosphoSitePlus
T1238 Phosphorylation PhosphoSitePlus
K1248 Ubiquitination PhosphoSitePlus
K1272 Ubiquitination PhosphoSitePlus
K1280 Ubiquitination PhosphoSitePlus
K1290 Ubiquitination PhosphoSitePlus
S1312 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S222 Phosphorylation HPRD 20068231
T406 Phosphorylation HPRD 18691976
S407 Phosphorylation HPRD 19413330, 18691976, 16964243, ...19664994, 19691289, 19007248, 18669648, 19415658, 20068231
S730 Phosphorylation HPRD 17525332
S782 Phosphorylation HPRD 19413330
T877 Phosphorylation HPRD 18691976
T892 Phosphorylation HPRD 17525332
S1060 Phosphorylation HPRD 18691976
S1061 Phosphorylation HPRD 17525332, 18077418, 20068231
T1250 Phosphorylation HPRD 20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047368 (hFANCI/Phos:1) pS556,pS559,pS565,pS617 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K4 N4 Biomuta DOID:363 / uterine cancer [ icgc ]
K16 T16 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K331 N331 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K715 N715 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]
S730 F730 Biomuta DOID:4159 / skin cancer [ cosmic ]
K780 E780 Biomuta DOID:4606 / bile duct cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S782 A782 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S782 F782 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K799 N799 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K869 N869 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T877 A877 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T892 S892 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K897 N897 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T952 S952 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1060 F1060 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
C1085 W1085 Biomuta [ cosmic ]
S1120 F1120 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T1250 A1250 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
K1272 * Biomuta DOID:3571 / liver cancer [ cosmic ]