Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NV79 / PCMD2_HUMAN
Protein Name Protein-L-isoaspartate O-methyltransferase domain-containing protein 2
Gene Name Name: PCMTD2
Synonyms:C20orf36;
Organism Homo sapiens (Human)

PRO ID PR:Q9NV79
DAG View
PRO Name protein-L-isoaspartate O-methyltransferase domain-containing protein 2 (human)
Definition A protein-L-isoaspartate O-methyltransferase domain-containing protein 2 that is encoded in the genome of human.
Short Label hPCMTD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NV79 (PCMTD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K124 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K257 Ubiquitination PhosphoSitePlus
T263 Phosphorylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
T274 Phosphorylation PhosphoSitePlus
K295 Ubiquitination PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K194 R194 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K194 M194 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S306 P306 Biomuta DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
S306 L306 Biomuta DOID:4606 / bile duct cancer [ cosmic ]