iPTMnet Report for Q9NUP7 (TRMT13)
Protein Information
UniProt AC / UniProt ID | Q9NUP7 / TRM13_HUMAN |
Protein Name | tRNA:m(4)X modification enzyme TRM13 homolog |
Gene Name | Name: TRMT13 Synonyms:CCDC76; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NUP7 |
PRO Name | tRNA:m(4)X modification enzyme TRM13 homolog (human) |
Definition | A tRNA guanosine-2'-O-methyltransferase TRM13 that is encoded in the genome of human. |
Short Label | hTRMT13 |
Category | organism-gene |
Q9NUP7 (TRMT13) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 19413330, 22223895, 20068231 | ||
S7 | Phosphorylation | score1 | PhosphoSitePlus | |||
S130 | Phosphorylation | score1 | PhosphoSitePlus | |||
K138 | Ubiquitination | score1 | PhosphoSitePlus | |||
K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
K178 | Ubiquitination | score1 | PhosphoSitePlus | |||
K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
S368 | Phosphorylation | score1 | PhosphoSitePlus | |||
S369 | Phosphorylation | score1 | PhosphoSitePlus | |||
T372 | Phosphorylation | score1 | PhosphoSitePlus | |||
T387 | Phosphorylation | score1 | PhosphoSitePlus | |||
S397 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y405 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
A2 | E2 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K138 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S397 | R397 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S397 | N397 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |