iPTMnet Report Q9NUI1 DECR2

Protein Information

Cytoscape View

UniProt AC / UniProt ID	Q9NUI1 / DECR2_HUMAN
Protein Name	Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
Gene Name	Name: DECR2 Synonyms:PDCR,SDR17C1;
Organism	Homo sapiens (Human)

PRO ID	PR:Q9NUI1 DAG View
PRO Name	peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (human)
Definition	A peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] that is encoded in the genome of human.
Short Label	hDECR2
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

Q9NUI1 (DECR2) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	A2	Acetylation		score1	UniProt	22814378
	K29	Ubiquitination		score1	PhosphoSitePlus
	S61	Phosphorylation		score1	PhosphoSitePlus
	T67	Phosphorylation		score1	PhosphoSitePlus
	K151	Acetylation		score2	PhosphoSitePlus UniProt	19608861
	S226	Phosphorylation		score1	PhosphoSitePlus
	T232	Phosphorylation		score1	PhosphoSitePlus
	S234	Phosphorylation		score1	PhosphoSitePlus
	S287	Phosphorylation		score2	PhosphoSitePlus UniProt	23186163
	S289	Phosphorylation		score1	PhosphoSitePlus
	K291	Acetylation		score2	PhosphoSitePlus UniProt	19608861

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S59	Phosphorylation		score0	HPRD	17081983
	S61	Phosphorylation		score0	HPRD	17081983
	T138	Phosphorylation		score0	HPRD	20068231

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
K151	N151	Biomuta		DOID:10534 / stomach cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
S226	N226	Biomuta		DOID:3571 / liver cancer [ cosmic ]