iPTMnet Report for Q9NTZ6 (RBM12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NTZ6 / RBM12_HUMAN
Protein Name RNA-binding protein 12
Gene Name Name: RBM12
Synonyms:KIAA0765;ORFNames:HRIHFB2091;
Organism Homo sapiens (Human)

PRO ID PR:Q9NTZ6
DAG View
PRO Name RNA-binding protein 12 (human)
Definition An RNA-binding protein 12 that is encoded in the genome of human.
Short Label hRBM12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NTZ6 (RBM12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T16 Phosphorylation PhosphoSitePlus
S67 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
S67 Phosphorylation PhosphoSitePlus
T70 Phosphorylation PhosphoSitePlus
T77 Phosphorylation PhosphoSitePlus
S103 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
S110 O-Glycosylation GlyGen 32574038, 31373491
S111 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 31373491, 32119511, 35289036, 29351928, 34229054, 36240223
S111 Phosphorylation PhosphoSitePlus
S114 O-Glycosylation GlyGen 32574038, 31373491
S115 O-Glycosylation GlyGen 32574038
T121 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
T122 O-Glycosylation GlyGen 23301498, 35138101, 25813380, ...31492838, 35289036, 29351928, 22661428, 34725712, 32119511, 31637018, 32574038, 32938750, 35132862, 27655845, 33214551, 30379171, 30059200, 35254053, 34019948, 36240223, 28510447, 34229054
S124 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...32938750, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 28510447, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
S130 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
S132 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
T135 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...32938750, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 28510447, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
T137 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
T138 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
S139 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
S143 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
T149 O-Glycosylation GlyGen 23301498, 27655845, 33214551, ...28510447, 35138101, 35254053, 31637018, 30379171, 32574038, 34725712, 34019948, 30059200, 35132862, 22661428, 31492838, 32119511, 35289036, 29351928, 34229054, 36240223
S204 Phosphorylation IEDB 35494241
K295 Sumoylation PhosphoSitePlus
K336 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus   UniProt 23186163
K361 Acetylation PhosphoSitePlus
Y371 Phosphorylation PhosphoSitePlus
S375 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
T378 Phosphorylation PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus
S415 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17287340, 20068231
S420 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17287340, 17081983
S422 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17287340, 17081983, ...18767875, 19651622, 18669648, 23186163, 20068231
S424 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 21406692, 17287340, ...18220336, 18767875, 17322306, 18669648, 23186163, 20068231
Y433 Phosphorylation HPRD   PhosphoSitePlus 19651622
K444 Ubiquitination PhosphoSitePlus
K451 Acetylation PhosphoSitePlus
K451 Ubiquitination PhosphoSitePlus
K485 Acetylation PhosphoSitePlus
K485 Methylation PhosphoSitePlus
K485 Ubiquitination PhosphoSitePlus
K507 Ubiquitination PhosphoSitePlus
S525 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y526 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15144186
K593 Sumoylation PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus
K893 Ubiquitination PhosphoSitePlus
R920 Methylation PhosphoSitePlus
R925 Methylation PhosphoSitePlus
K926 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T77 M77 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T135 A135 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S415 I415 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S415 N415 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S420 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S422 * Biomuta DOID:1612 / breast cancer [ cosmic ]
K451 R451 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K451 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
K485 R485 Biomuta DOID:3571 / liver cancer [ cosmic ]
K485 Q485 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K507 R507 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y526 C526 Biomuta DOID:2531 / hematologic cancer [ cosmic ]