iPTMnet Report for Q9NSD7 (RXFP3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NSD7 / RL3R1_HUMAN
Protein Name Relaxin-3 receptor 1
Gene Name Name: RXFP3
Synonyms:GPCR135,RLN3R1,SALPR;
Organism Homo sapiens (Human)

PRO ID PR:Q9NSD7
DAG View
PRO Name relaxin-3 receptor 1 (human)
Definition A relaxin-3 receptor 1 that is encoded in the genome of human.
Short Label hRXFP3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NSD7 (RXFP3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S269 Phosphorylation PhosphoSitePlus
R312 Methylation PhosphoSitePlus
R320 Methylation PhosphoSitePlus
Y460 Phosphorylation PhosphoSitePlus
Y469 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R312 P312 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R312 L312 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R312 C312 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
R320 S320 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R320 * Biomuta DOID:3571 / liver cancer [ cosmic ]
R320 I320 Biomuta DOID:1319 / brain cancer [ icgc ]
Y460 F460 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]