iPTMnet Report for Q9NRX5 (SERINC1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NRX5 / SERC1_HUMAN
Protein Name Serine incorporator 1
Gene Name Name: SERINC1
Synonyms:KIAA1253,TDE1L,TDE2;ORFNames:UNQ396/PRO732;
Organism Homo sapiens (Human)

PRO ID PR:Q9NRX5
DAG View
PRO Name serine incorporator 1 (human)
Definition A serine incorporator 1 that is encoded in the genome of human.
Short Label hSERINC1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NRX5 (SERINC1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
G2 Myristoylation UniProt 24223779, 20213681
S31 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
T36 Phosphorylation PhosphoSitePlus
T38 Phosphorylation PhosphoSitePlus
N298 N-Glycosylation GlyGen   UniProt 19159218
K343 Ubiquitination PhosphoSitePlus
T345 Phosphorylation PhosphoSitePlus
T347 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S351 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
T352 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18578522, ...20068231
S361 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 17081983, ...18578522
S364 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 18578522
Y410 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S413 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S418 Phosphorylation HPRD   PhosphoSitePlus 20068231
T421 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S31 R31 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S31 C31 Biomuta DOID:1324 / lung cancer [ cosmic ]
T36 A36 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T36 S36 Biomuta DOID:1324 / lung cancer [ cosmic ]
S361 C361 Biomuta DOID:3571 / liver cancer [ cosmic ]
S361 G361 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y410 C410 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S418 R418 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S418 I418 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]