iPTMnet Report for Q9NRW7 (VPS45)
Protein Information
UniProt AC / UniProt ID | Q9NRW7 / VPS45_HUMAN |
Protein Name | Vacuolar protein sorting-associated protein 45 |
Gene Name | Name: VPS45 Synonyms:VPS45A,VPS45B; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NRW7 |
PRO Name | vacuolar protein sorting-associated protein 45 (human) |
Definition | A vacuolar protein sorting-associated protein 45 that is encoded in the genome of human. |
Short Label | hVPS45 |
Category | organism-gene |
Q9NRW7 (VPS45) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y10 | Phosphorylation | score1 | PhosphoSitePlus | |||
K76 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y81 | Phosphorylation | score1 | PhosphoSitePlus | |||
S168 | Phosphorylation | score1 | PhosphoSitePlus | |||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
K192 | Ubiquitination | score1 | PhosphoSitePlus | |||
K197 | Ubiquitination | score1 | PhosphoSitePlus | |||
K257 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y272 | Phosphorylation | score1 | PhosphoSitePlus | |||
K296 | Ubiquitination | score1 | PhosphoSitePlus | |||
K304 | Ubiquitination | score1 | PhosphoSitePlus | |||
S307 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163, 24275569 | ||
K312 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y318 | Phosphorylation | score1 | PhosphoSitePlus | |||
K322 | Methylation | score1 | PhosphoSitePlus | |||
K322 | Ubiquitination | score1 | PhosphoSitePlus | |||
K323 | Methylation | score1 | PhosphoSitePlus | |||
T327 | Phosphorylation | score1 | PhosphoSitePlus | |||
K330 | Ubiquitination | score1 | PhosphoSitePlus | |||
S339 | Phosphorylation | score1 | PhosphoSitePlus | |||
K371 | Ubiquitination | score1 | PhosphoSitePlus | |||
K378 | Ubiquitination | score1 | PhosphoSitePlus | |||
K418 | Ubiquitination | score1 | PhosphoSitePlus | |||
S424 | Phosphorylation | score1 | PhosphoSitePlus | |||
K432 | Ubiquitination | score1 | PhosphoSitePlus | |||
S437 | Phosphorylation | score1 | PhosphoSitePlus | |||
S441 | Phosphorylation | score1 | PhosphoSitePlus | |||
K443 | Ubiquitination | score1 | PhosphoSitePlus | |||
K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
K454 | Ubiquitination | score1 | PhosphoSitePlus | |||
K457 | Ubiquitination | score1 | PhosphoSitePlus | |||
K479 | Ubiquitination | score1 | PhosphoSitePlus | |||
K483 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y487 | Phosphorylation | score1 | PhosphoSitePlus | |||
K557 | Ubiquitination | score1 | PhosphoSitePlus | |||
S559 | Phosphorylation | score1 | PhosphoSitePlus | |||
S560 | Phosphorylation | score1 | PhosphoSitePlus | |||
T563 | Phosphorylation | score1 | PhosphoSitePlus | |||
S564 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y10 | H10 | Biomuta | [ cosmic ] | |
Y10 | C10 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K76 | N76 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K312 | M312 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S339 | P339 | Biomuta | DOID:363 / uterine cancer [ cosmic ] | |
K432 | E432 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S441 | R441 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
K457 | T457 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
Y487 | F487 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S564 | * | Biomuta | DOID:4159 / skin cancer [ cosmic ] |