iPTMnet Report for Q9NRA8 (EIF4ENIF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NRA8 / 4ET_HUMAN
Protein Name Eukaryotic translation initiation factor 4E transporter
Gene Name Name: EIF4ENIF1
Organism Homo sapiens (Human)

PRO ID PR:Q9NRA8
DAG View
PRO Name eukaryotic translation initiation factor 4E transporter (human)
Definition A eukaryotic translation initiation factor 4E transporter that is encoded in the genome of human.
Short Label hEIF4ENIF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NRA8 (EIF4ENIF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S24 Phosphorylation PhosphoSitePlus
Y30 Phosphorylation PhosphoSitePlus
T31 Phosphorylation PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
Y71 Phosphorylation PhosphoSitePlus
S74 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S77 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus   UniProt 23186163
S82 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
S115 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus   UniProt 22028470, 23186163
S120 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S136 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S138 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S144 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
K202 Acetylation PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
T215 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
T227 Phosphorylation PhosphoSitePlus
T253 Phosphorylation PhosphoSitePlus
T257 Phosphorylation PhosphoSitePlus
S259 Phosphorylation PhosphoSitePlus
S301 Phosphorylation P45983 (MAPK8) PhosphoSitePlus   Signor   UniProt 22966201, 20068231
S321 Phosphorylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
S342 Phosphorylation PhosphoSitePlus
S345 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S351 Phosphorylation PhosphoSitePlus
S352 Phosphorylation PhosphoSitePlus
S353 Phosphorylation PhosphoSitePlus   UniProt 24275569
S356 Phosphorylation PhosphoSitePlus
T357 Phosphorylation PhosphoSitePlus
S374 Phosphorylation P45983 (MAPK8) PhosphoSitePlus   Signor   UniProt 22966201
S379 Phosphorylation PhosphoSitePlus
Y382 Phosphorylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
K406 Ubiquitination PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus   UniProt 23186163
K420 Ubiquitination PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
K446 Ubiquitination PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
S454 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
T465 Phosphorylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
K477 Ubiquitination PhosphoSitePlus
K486 Acetylation PhosphoSitePlus   UniProt 19608861
K486 Ubiquitination PhosphoSitePlus
K492 Methylation PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
T496 Phosphorylation PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus
K502 Ubiquitination PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus
S513 Phosphorylation P45983 (MAPK8) phospho.ELM   PhosphoSitePlus   Signor   UniProt 22966201, 18669648, 23186163, ...20068231
S541 Phosphorylation PhosphoSitePlus
S564 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S568 Phosphorylation PhosphoSitePlus
R574 Methylation PhosphoSitePlus
S577 Phosphorylation PhosphoSitePlus
Y580 Phosphorylation PhosphoSitePlus
R582 Methylation PhosphoSitePlus
R584 Methylation PhosphoSitePlus
S587 Phosphorylation P45983 (MAPK8) PhosphoSitePlus   Signor   UniProt 22966201, 23186163, 19690332
T592 Phosphorylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
T614 Phosphorylation PhosphoSitePlus
S618 Phosphorylation PhosphoSitePlus
S670 Phosphorylation IEDB   PhosphoSitePlus 27869121
S680 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S681 Phosphorylation PhosphoSitePlus
S693 Phosphorylation P45983 (MAPK8) phospho.ELM   PhosphoSitePlus   Signor   UniProt 18669648, 22966201, 19690332
K732 Ubiquitination PhosphoSitePlus
S746 Phosphorylation PhosphoSitePlus
S751 Phosphorylation PhosphoSitePlus
S752 Phosphorylation P45983 (MAPK8) PhosphoSitePlus   Signor   UniProt 22966201
T754 Phosphorylation PhosphoSitePlus
T755 Phosphorylation PhosphoSitePlus
S757 Phosphorylation phospho.ELM 18669648
K758 Ubiquitination PhosphoSitePlus
S765 Phosphorylation PhosphoSitePlus
S766 Phosphorylation PhosphoSitePlus
S768 Phosphorylation PhosphoSitePlus
T769 Phosphorylation PhosphoSitePlus
S772 O-Glycosylation GlyGen 31492838
S772 Phosphorylation PhosphoSitePlus
R776 Methylation PhosphoSitePlus
K779 Ubiquitination PhosphoSitePlus
T792 Phosphorylation PhosphoSitePlus
T891 Phosphorylation PhosphoSitePlus
S905 O-Glycosylation GlyGen 34846842
S912 Phosphorylation PhosphoSitePlus
S914 O-Glycosylation GlyGen 31492838
S914 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
S920 O-Glycosylation GlyGen 34846842
S920 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087
T924 Phosphorylation PhosphoSitePlus
S946 Phosphorylation PhosphoSitePlus
R948 Methylation PhosphoSitePlus
S951 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 18669648, ...24275569, 20068231
S977 Phosphorylation PhosphoSitePlus
Y983 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation HPRD 18669648, 20068231
S69 Phosphorylation HPRD 20068231
S74 Phosphorylation HPRD 19651622, 20068231
S77 Phosphorylation HPRD 20068231
S78 Phosphorylation HPRD 19651622, 19691289, 20068231
S120 Phosphorylation HPRD 18669648
S136 Phosphorylation HPRD 18669648
S138 Phosphorylation HPRD 18669648
S301 Phosphorylation HPRD 20068231
S345 Phosphorylation HPRD 18669648, 19664995, 20068231
S374 Phosphorylation HPRD 20068231
S414 Phosphorylation HPRD 20068231
S417 Phosphorylation HPRD 20068231
T482 Phosphorylation HPRD 20068231
S494 Phosphorylation HPRD 18691976
T496 Phosphorylation HPRD 18691976
S513 Phosphorylation HPRD 18669648, 20068231
S564 Phosphorylation HPRD 19413330, 17322306, 18212344, ...18767875, 19664994, 19664995, 19691289, 19651622, 18669648, 20068231
S568 Phosphorylation HPRD 20068231
S587 Phosphorylation HPRD 17322306, 20068231
S670 Phosphorylation HPRD 19691289
S680 Phosphorylation HPRD 18669648
S693 Phosphorylation HPRD 18669648
S757 Phosphorylation HPRD 18669648
S914 Phosphorylation HPRD 18088087
S920 Phosphorylation HPRD 18088087
S951 Phosphorylation HPRD 17322306, 18669648, 19691289, ...20068231
Site PTM Type PTM Enzyme Score Source PMID
S436 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K39 E39 Biomuta DOID:1324 / lung cancer [ cosmic ]
S213 Y213 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S223 Y223 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S321 P321 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S321 L321 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S342 C342 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S342 F342 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S353 N353 Biomuta DOID:4159 / skin cancer [ cosmic ]
S374 C374 Biomuta DOID:1781 / thyroid cancer [ icgc ]
T482 N482 Biomuta DOID:3571 / liver cancer [ cosmic ]
K492 R492 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S541 F541 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S564 A564 Biomuta DOID:3571 / liver cancer [ cosmic ]
S568 L568 Biomuta DOID:3571 / liver cancer [ cosmic ]
R574 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R574 Q574 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S752 F752 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T754 I754 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S757 Y757 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S766 L766 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S768 F768 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S772 Y772 Biomuta DOID:363 / uterine cancer [ icgc ]
R776 H776 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ cosmic, icgc ]
R776 C776 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K779 E779 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]