Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NR64 / KLHL1_HUMAN
Protein Name Kelch-like protein 1
Gene Name Name: KLHL1
Synonyms:KIAA1490;
Organism Homo sapiens (Human)

PRO ID PR:Q9NR64
DAG View
PRO Name kelch-like protein 1 (human)
Definition A kelch-like protein 1 that is encoded in the genome of human.
Short Label hKLHL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NR64 (KLHL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S75 Phosphorylation PhosphoSitePlus
S76 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S78 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
T444 O-Glycosylation GlyGen 30379171
K518 Ubiquitination PhosphoSitePlus
T519 Phosphorylation PhosphoSitePlus
T522 Phosphorylation PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
T530 Phosphorylation PhosphoSitePlus
T532 Phosphorylation PhosphoSitePlus
Y556 Phosphorylation PhosphoSitePlus
T624 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S75 T75 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S76 C76 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S77 T77 Biomuta DOID:1324 / lung cancer [ cosmic ]
T444 I444 Biomuta DOID:363 / uterine cancer [ icgc ]
T519 K519 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T522 S522 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T530 I530 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y556 D556 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]