iPTMnet Report for Q9NQI0 (DDX4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NQI0 / DDX4_HUMAN
Protein Name Probable ATP-dependent RNA helicase DDX4
Gene Name Name: DDX4
Synonyms:VASA;
Organism Homo sapiens (Human)

PRO ID PR:Q9NQI0
DAG View
PRO Name probable ATP-dependent RNA helicase DDX4 (human)
Definition A probable ATP-dependent RNA helicase DDX4 that is encoded in the genome of human.
Short Label hDDX4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NQI0 (DDX4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T37 Phosphorylation PhosphoSitePlus
K75 Acetylation PhosphoSitePlus
K89 Acetylation PhosphoSitePlus
S90 Phosphorylation PhosphoSitePlus
Y133 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
T312 Phosphorylation PhosphoSitePlus
S336 Phosphorylation PhosphoSitePlus
T339 Phosphorylation PhosphoSitePlus
Y400 Phosphorylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
K432 Acetylation PhosphoSitePlus
Y442 Phosphorylation PhosphoSitePlus
K530 Acetylation PhosphoSitePlus
T549 O-Glycosylation GlyGen 30379171
Site PTM Type PTM Enzyme Score Source PMID
S11 Phosphorylation PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
S77 Phosphorylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S11 Y11 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S14 F14 Biomuta DOID:4159 / skin cancer [ cosmic ]
S80 * Biomuta DOID:1781 / thyroid gland cancer [ cosmic ]
S80 L80 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K89 N89 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S90 N90 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S139 L139 Biomuta DOID:4159 / skin cancer [ cosmic ]
K530 Q530 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K530 R530 Biomuta DOID:9256 / colorectal cancer [ cosmic ]