iPTMnet Report for Q9NQG5 (RPRD1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NQG5 / RPR1B_HUMAN
Protein Name Regulation of nuclear pre-mRNA domain-containing protein 1B
Gene Name Name: RPRD1B
Synonyms:C20orf77,CREPT;
Organism Homo sapiens (Human)

PRO ID PR:Q9NQG5
DAG View
PRO Name regulation of nuclear pre-mRNA domain-containing protein 1B (human)
Definition A regulation of nuclear pre-mRNA domain-containing protein 1B that is encoded in the genome of human.
Short Label hRPRD1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NQG5 (RPRD1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22223895
S2 Phosphorylation RLIMS-P 24997600
S3 Phosphorylation PhosphoSitePlus
S7 Phosphorylation RLIMS-P 24997600
K11 Ubiquitination PhosphoSitePlus
K12 Sumoylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
S128 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P 30518842, 17081983
S132 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231, 24275569
S134 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17322306, 17287340, 18767875, ...18452278, 19651622, 18669648, 24275569, 18707149, 23186163, 20068231
S145 Phosphorylation PhosphoSitePlus   RLIMS-P 30518842
Y161 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S164 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983, 20068231
Y165 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983
S166 Phosphorylation P42345 (MTOR) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18491316, 17081983, 15302935, ...19664995, 18452278, 19651622, 18669648, 21659604, 19415658, 20068231
S171 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T177 Phosphorylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
K216 Ubiquitination PhosphoSitePlus
T218 Phosphorylation RLIMS-P 30518842
S227 Phosphorylation RLIMS-P 30518842
C234 S-Nitrosylation dbSNO 26338901
R251 Methylation PhosphoSitePlus
T262 Phosphorylation PhosphoSitePlus
S270 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y117 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S128 P128 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y161 H161 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S166 F166 Biomuta DOID:4159 / skin cancer [ cosmic ]
K216 N216 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R251 H251 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R251 C251 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]