iPTMnet Report for Q9NQC7 (CYLD)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NQC7 / CYLD_HUMAN
Protein Name Ubiquitin carboxyl-terminal hydrolase CYLD
Gene Name Name: CYLD
Synonyms:CYLD1,KIAA0849;ORFNames:HSPC057;
Organism Homo sapiens (Human)

PRO ID PR:Q9NQC7
DAG View
PRO Name ubiquitin carboxyl-terminal hydrolase CYLD (human)
Definition A ubiquitin carboxyl-terminal hydrolase CYLD that is encoded in the genome of human.
Short Label hCYLD
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NQC7 (CYLD) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
T12 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
Y15 Phosphorylation PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
T31 Phosphorylation PhosphoSitePlus
T35 Phosphorylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
K318 Ubiquitination PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
T343 Phosphorylation PhosphoSitePlus
S344 Phosphorylation PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
S362 Phosphorylation Q13554 (CAMK2B) , Q9UQM7 (CAMK2A) PhosphoSitePlus   RLIMS-P   Signor 24614225
S369 Phosphorylation PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
Y376 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus   UniProt 24275569
T389 Phosphorylation PhosphoSitePlus
S392 Phosphorylation PhosphoSitePlus
T393 Phosphorylation phospho.ELM 18669648
S399 Phosphorylation PhosphoSitePlus
S409 Phosphorylation PhosphoSitePlus
S418 Phosphorylation O14920 (IKBKB) , O15111 (CHUK) , Q14164 (IKBKE) , Q13554 (CAMK2B) neXtProt   PRO   PhosphoSitePlus   RLIMS-P   Signor   UniProt 23186163, 19481526, 29755980, ...15870263, 32024820, 24614225, 24961988
S422 Phosphorylation O14920 (IKBKB) , O15111 (CHUK) PhosphoSitePlus   RLIMS-P   Signor   UniProt 24961988, 24614225, 23186163, ...15870263
T424 Phosphorylation PhosphoSitePlus
S432 Phosphorylation O14920 (IKBKB) , O15111 (CHUK) PhosphoSitePlus   RLIMS-P   Signor 24961988, 24614225, 15870263
S436 Phosphorylation O14920 (IKBKB) , O15111 (CHUK) PhosphoSitePlus   RLIMS-P   Signor 24961988, 24614225, 15870263
S439 Phosphorylation O14920 (IKBKB) , O15111 (CHUK) PhosphoSitePlus   Signor 24614225, 15870263
S441 Phosphorylation O15111 (CHUK) , O14920 (IKBKB) PhosphoSitePlus   Signor 24614225, 15870263
S444 Phosphorylation O14920 (IKBKB) , O15111 (CHUK) PhosphoSitePlus   Signor 24614225, 15870263
Y523 Phosphorylation PhosphoSitePlus
K530 Ubiquitination PhosphoSitePlus
S547 Phosphorylation PhosphoSitePlus
S552 Phosphorylation PhosphoSitePlus
C558 Methylation IEDB 31844290
S560 Phosphorylation PhosphoSitePlus
S568 Phosphorylation PhosphoSitePlus   RLIMS-P 35958947
K627 Ubiquitination PhosphoSitePlus
K668 Ubiquitination PhosphoSitePlus
K701 Ubiquitination PhosphoSitePlus
C751 Methylation IEDB 31844290
K761 Ubiquitination PhosphoSitePlus
K768 Ubiquitination PhosphoSitePlus
S772 Phosphorylation Q13554 (CAMK2B) , Q9UQM7 (CAMK2A) PhosphoSitePlus   RLIMS-P   Signor 24614225
K818 Ubiquitination PhosphoSitePlus
K829 Ubiquitination PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
K842 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T393 Phosphorylation HPRD 18669648
S399 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
T390 Phosphorylation HPRD 18669648
S396 Phosphorylation HPRD 17081983


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000047122 (hCYLD/Phos:1) pS418 PRO