iPTMnet Report for Q9NQB0 (TCF7L2)
Protein Information
UniProt AC / UniProt ID | Q9NQB0 / TF7L2_HUMAN |
Protein Name | Transcription factor 7-like 2 |
Gene Name | Name: TCF7L2 Synonyms:TCF4; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NQB0 |
PRO Name | transcription factor 7-like 2 (human) |
Definition | A transcription factor 7-like 2 that is encoded in the genome of human. |
Short Label | hTCF7L2 |
Category | organism-gene |
Q9NQB0 (TCF7L2) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K22 | Sumoylation | score1 | PhosphoSitePlus | |||
S35 | Phosphorylation | score1 | PhosphoSitePlus | |||
S58 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11711551 | ||
S59 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11711551 | ||
S60 | Phosphorylation | score3 | phospho.ELM PhosphoSitePlus | 11711551 | ||
S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
S79 | Phosphorylation | score1 | PhosphoSitePlus | |||
S82 | Phosphorylation | score1 | PhosphoSitePlus | |||
K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
R126 | Methylation | score1 | PhosphoSitePlus | |||
Y151 | Phosphorylation | score1 | PhosphoSitePlus | |||
K173 | Acetylation | score1 | PhosphoSitePlus | |||
S177 | Phosphorylation | Q9UKE5 (TNIK) | score3 | neXtProt PhosphoSitePlus Signor | 20530691 | |
S179 | Phosphorylation | score1 | PhosphoSitePlus | |||
T201 | Phosphorylation | Q9UBE8 (NLK) | score3 | neXtProt PRO PhosphoSitePlus Signor UniProt | 12556497 | |
T212 | Phosphorylation | Q9UBE8 (NLK) | score3 | neXtProt PRO PhosphoSitePlus Signor UniProt | 12556497 | |
S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
K335 | Acetylation | score1 | PhosphoSitePlus | |||
K335 | Ubiquitination | score1 | PhosphoSitePlus | |||
K352 | Ubiquitination | score1 | PhosphoSitePlus | |||
K362 | Acetylation | score1 | PhosphoSitePlus | |||
K362 | Ubiquitination | score1 | PhosphoSitePlus | |||
K367 | Acetylation | score1 | PhosphoSitePlus | |||
C372 | Methylation | score1 | IEDB | 33981976, 31844290 | ||
K398 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y399 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y400 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y414 | Phosphorylation | score1 | PhosphoSitePlus | |||
S418 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y489 | Phosphorylation | score1 | PhosphoSitePlus | |||
K563 | Acetylation | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
K433 | Sumoylation | score1 | PhosphoSitePlus | |||
K442 | Sumoylation | score1 | PhosphoSitePlus |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000049408 (hTCF7L2/Phos:1) | pT201,pT212 | PRO |
Proteoform PPIs
Protein 1 | Relation | Protein 2 | Source | PMID | |
---|---|---|---|---|---|
PR:000037190 (hCTNNB1/iso:1/Phos:7) | decreased Interaction | PR:Q9NQB0 (hTCF7L2) | PRO | 23617586 |