iPTMnet Report for Q9NPR2 (SEMA4B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9NPR2 / SEM4B_HUMAN
Protein Name Semaphorin-4B precursor
Gene Name Name: SEMA4B
Synonyms:KIAA1745;ORFNames:UNQ749/PRO1480;
Organism Homo sapiens (Human)

PRO ID PR:Q9NPR2
DAG View
PRO Name semaphorin-4B (human)
Definition A semaphorin-4B that is encoded in the genome of human.
Short Label hSEMA4B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9NPR2 (SEMA4B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N69 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 29391424, ...24190977
Y70 Phosphorylation PhosphoSitePlus
T71 Phosphorylation PhosphoSitePlus
K408 Acetylation PhosphoSitePlus
N410 N-Glycosylation GlyGen   UniProt 16335952, 23090970, 29391424, ...24190977
N525 N-Glycosylation GlyGen 23090970, 24190977
S582 O-Glycosylation GlyGen 30459171
S699 Phosphorylation PhosphoSitePlus
K745 Ubiquitination PhosphoSitePlus
K749 Ubiquitination PhosphoSitePlus
T769 Phosphorylation PhosphoSitePlus
S779 Phosphorylation PhosphoSitePlus
T780 Phosphorylation PhosphoSitePlus
Y787 Phosphorylation PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus
S791 Phosphorylation PhosphoSitePlus
S793 Phosphorylation PhosphoSitePlus   UniProt 23186163
T801 Phosphorylation PhosphoSitePlus
K805 Ubiquitination PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
S813 Phosphorylation PhosphoSitePlus
S818 Phosphorylation PhosphoSitePlus   UniProt 17081983
S830 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 17081983
S835 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S793 Phosphorylation HPRD 19664994, 18212344
S818 Phosphorylation HPRD 17081983
S830 Phosphorylation HPRD 19651622, 18669648, 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S582 L582 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S699 R699 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S793 R793 Biomuta DOID:1612 / breast cancer [ cosmic ]
T801 S801 Biomuta DOID:1319 / brain cancer [ cosmic ]
K805 E805 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S809 N809 Biomuta DOID:1324 / lung cancer [ cosmic ]
S818 F818 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S830 L830 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]