iPTMnet Report for Q9NPQ8 (RIC8A)
Protein Information
UniProt AC / UniProt ID | Q9NPQ8 / RIC8A_HUMAN |
Protein Name | Synembryn-A |
Gene Name | Name: RIC8A |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NPQ8 |
PRO Name | synembryn-A (human) |
Definition | A synembryn-A that is encoded in the genome of human. |
Short Label | hRIC8A |
Category | organism-gene |
Q9NPQ8 (RIC8A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T12 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y25 | Phosphorylation | score1 | PhosphoSitePlus | |||
S30 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 17525332 | ||
S32 | Phosphorylation | score1 | PhosphoSitePlus | |||
S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
T193 | Phosphorylation | score1 | PhosphoSitePlus | |||
T195 | Phosphorylation | score1 | PhosphoSitePlus | |||
T199 | Phosphorylation | score1 | PhosphoSitePlus | |||
T203 | Phosphorylation | score1 | PhosphoSitePlus | |||
T324 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 27869121 | ||
K328 | Ubiquitination | score1 | PhosphoSitePlus | |||
K353 | Ubiquitination | score1 | PhosphoSitePlus | |||
K409 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y435 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 27096001 | ||
S436 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 23186163, 27096001, 18669648, ... | ||
T441 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P UniProt | 23186163, 27096001, 18669648, ... | ||
T443 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 27096001 | ||
Y446 | Phosphorylation | score1 | PhosphoSitePlus | |||
K450 | Ubiquitination | score1 | PhosphoSitePlus | |||
S452 | Phosphorylation | score1 | PhosphoSitePlus | |||
T485 | Phosphorylation | score1 | PhosphoSitePlus | |||
K489 | Ubiquitination | score1 | PhosphoSitePlus | |||
S491 | Phosphorylation | score1 | PhosphoSitePlus | |||
S502 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 21406692, 23186163, 20068231 | ||
S523 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 24275569 | ||
S524 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648, 24275569 | ||
S528 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18669648 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S30 | Phosphorylation | score0 | HPRD | 17525332, 18077418 | ||
Y441 | Phosphorylation | score0 | HPRD | 18691976, 19651622, 18669648, ... | ||
S442 | Phosphorylation | score0 | HPRD | 18691976, 19664994, 19651622, ... | ||
T447 | Phosphorylation | score0 | HPRD | 18691976, 19651622, 18669648, ... | ||
T449 | Phosphorylation | score0 | HPRD | 19651622, 18669648, 19664994 | ||
Y452 | Phosphorylation | score0 | HPRD | 20166139, 18669648 | ||
S508 | Phosphorylation | score0 | HPRD | 18691976, 18669648, 18212344, ... | ||
S529 | Phosphorylation | score0 | HPRD | 18669648 | ||
S530 | Phosphorylation | score0 | HPRD | 18669648 | ||
S534 | Phosphorylation | score0 | HPRD | 18669648 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S74 | Y74 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S74 | P74 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
T199 | M199 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc, tcga ] | |
T203 | A203 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T441 | K441 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
T441 | A441 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
Y446 | N446 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T447 | K447 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
T447 | A447 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
Y452 | N452 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
T485 | N485 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] | |
S523 | F523 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
S529 | F529 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] |