iPTMnet Report for Q9NPF4 (OSGEP)
Protein Information
UniProt AC / UniProt ID | Q9NPF4 / OSGEP_HUMAN |
Protein Name | tRNA N6-adenosine threonylcarbamoyltransferase |
Gene Name | Name: OSGEP Synonyms:GCPL1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NPF4 |
PRO Name | tRNA N6-adenosine threonylcarbamoyltransferase (human) |
Definition | A tRNA N6-adenosine threonylcarbamoyltransferase that is encoded in the genome of human. |
Short Label | hOSGEP |
Category | organism-gene |
Q9NPF4 (OSGEP) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S10 | Phosphorylation | score1 | PhosphoSitePlus | |||
K13 | Ubiquitination | score1 | PhosphoSitePlus | |||
K23 | Acetylation | score1 | PhosphoSitePlus | |||
K23 | Ubiquitination | score1 | PhosphoSitePlus | |||
S88 | Phosphorylation | score1 | IEDB | 32387766 | ||
T127 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y130 | Phosphorylation | score1 | PhosphoSitePlus | |||
S132 | Phosphorylation | score1 | PhosphoSitePlus | |||
K169 | Ubiquitination | score1 | PhosphoSitePlus | |||
K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
K189 | Ubiquitination | score1 | PhosphoSitePlus | |||
S209 | Phosphorylation | score1 | PhosphoSitePlus | |||
T221 | Phosphorylation | score1 | PhosphoSitePlus | |||
T225 | Phosphorylation | score1 | PhosphoSitePlus | |||
C230 | Methylation | score1 | IEDB | 31844290 | ||
S318 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K185 | R185 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
K189 | T189 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
T221 | I221 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
S318 | F318 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |