iPTMnet Report for Q9NPC3 (CCNB1IP1)
Protein Information
UniProt AC / UniProt ID | Q9NPC3 / CIP1_HUMAN |
Protein Name | E3 ubiquitin-protein ligase CCNB1IP1 |
Gene Name | Name: CCNB1IP1 Synonyms:C14orf18,HEI10; |
Organism | Homo sapiens (Human) |
PRO ID | PR:Q9NPC3 |
PRO Name | E3 ubiquitin-protein ligase CCNB1IP1 (human) |
Definition | An E3 ubiquitin-protein ligase CCNB1IP1 that is encoded in the genome of human. |
Short Label | hCCNB1IP1 |
Category | organism-gene |
Q9NPC3 (CCNB1IP1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
Y125 | Phosphorylation | score1 | PhosphoSitePlus | |||
K132 | Ubiquitination | score1 | PhosphoSitePlus | |||
K154 | Ubiquitination | score1 | PhosphoSitePlus | |||
S158 | Phosphorylation | score0 | HPRD | 18767875 | ||
S161 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y178 | Phosphorylation | score2 | HPRD PhosphoSitePlus | 17322306 | ||
S180 | Phosphorylation | score1 | PhosphoSitePlus | |||
T221 | Phosphorylation | score1 | PhosphoSitePlus | |||
S257 | Phosphorylation | score1 | HPRD | 12612082 | ||
S259 | Phosphorylation | score1 | HPRD | 12612082 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
Y125 | C125 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] | |
Y125 | H125 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] | |
K154 | N154 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |