iPTMnet Report for Q9NP56 (PDE7B)
Protein Information
| UniProt AC / UniProt ID | Q9NP56 / PDE7B_HUMAN |
| Protein Name | cAMP-specific 3',5'-cyclic phosphodiesterase 7B |
| Gene Name | Name: PDE7B |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:Q9NP56 |
| PRO Name | cAMP-specific 3',5'-cyclic phosphodiesterase 7B (human) |
| Definition | A cAMP-specific 3',5'-cyclic phosphodiesterase 7B that is encoded in the genome of human. |
| Short Label | hPDE7B |
| Category | organism-gene |
DAG ViewQ9NP56 (PDE7B) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S45 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18220336 | ||
| S74 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T268 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S277 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K295 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K301 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S396 | Phosphorylation | score1 | IEDB | 32387766 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T268 | I268 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ icgc ] DOID:1612 / breast cancer [ cosmic ] | |
| S277 | T277 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| S277 | F277 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S396 | R396 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] |
