iPTMnet Report for Q9JLN9 (Mtor)


Protein Information

Cytoscape View


UniProt AC / UniProt ID Q9JLN9 / MTOR_MOUSE
Protein Name Serine/threonine-protein kinase mTOR
Gene Name Name: Mtor
Synonyms:Frap,Frap1;
Organism Mus musculus (Mouse)

PRO ID PR:Q9JLN9
DAG View
PRO Name serine/threonine-protein kinase mTOR (mouse)
Definition A serine/threonine-protein kinase mTOR that is encoded in the genome of mouse.
Short Label mMTOR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


Q9JLN9 (Mtor) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K230 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
Y858 Phosphorylation PhosphoSitePlus
Y861 Phosphorylation PhosphoSitePlus
T880 Phosphorylation PhosphoSitePlus
K898 Ubiquitination PhosphoSitePlus
K900 Ubiquitination PhosphoSitePlus
T1162 Phosphorylation PhosphoSitePlus
K1218 Ubiquitination PhosphoSitePlus
K1256 Ubiquitination PhosphoSitePlus
K1257 Ubiquitination PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus   UniProt 21183079, 19487463
T1262 Phosphorylation PhosphoSitePlus
K1293 Ubiquitination PhosphoSitePlus
K1400 Ubiquitination PhosphoSitePlus
K1406 Ubiquitination PhosphoSitePlus
S1418 Phosphorylation PhosphoSitePlus
K1465 Ubiquitination PhosphoSitePlus
K1471 Ubiquitination PhosphoSitePlus
K1511 Ubiquitination PhosphoSitePlus
K1655 Ubiquitination PhosphoSitePlus
K2066 Ubiquitination PhosphoSitePlus
S2069 Phosphorylation PhosphoSitePlus
S2159 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 34245780, 29150432
K2370 Ubiquitination PhosphoSitePlus
S2442 Phosphorylation PhosphoSitePlus
T2444 Phosphorylation PhosphoSitePlus
T2446 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P 29854093, 28638048, 31998287, ...26314207, 14970221, 32207633
S2448 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 30569110, 30973211, 26299806, ...32498424, 21949739, 29574227, 24187137, 32399718, 30409162, 24062605, 25716553, 26359501, 27781091, 28151473, 26597054, 32231246, 33741019, 31998287, 29554968, 28980850, 32316601, 27930667, 16086373, 33637094, 28810557, 26222260, 24391749, 27257474, 23071621, 28364027, 26267903, 31207499, 29854093, 28333151, 19291319, 30014636, 24967341, 28467426, 32751882, 29723221, 25439029, 23440873, 30696333, 25280966, 31726709, 24809512, 27599409, 32716920, 28718972, 30622053, 23409704, 31519159, 33184378, 32207633, 33918604, 18767117, 22359505, 30410750, 30876754, 28464882, 29734780, 26728896, 33658993, 24682776, 28638048, 31138988, 26858121, 23342114, 33071755, 30787203, 29623927, 30961637, 30410062, 26745759, 29720580, 28938574, 32107468, 25991723, 31159888, 14970221, 34217376, 24280377, 17978888, 21927580, 26312014, 24647338
Y2449 Phosphorylation PhosphoSitePlus
S2450 Phosphorylation PhosphoSitePlus
S2454 Phosphorylation PhosphoSitePlus
T2473 Phosphorylation PhosphoSitePlus
T2474 Phosphorylation PhosphoSitePlus
S2478 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17242355, 21183079
S2481 Phosphorylation Q9JLN9 (Mtor) IntAct   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 31373126, 28638048, 31726709, ...26314207, 26299806, 17242355, 32716920, 29720580, 29854093, 30622053, 31519159, 21183079, 21045808, 32207633, 28938574, 27781091, 25991723, 31207499, 31213901, 30410750, 29734780, 17978888, 29858083, 29554968, 31998287, 24647338, 23440873, 20022946, 26795633
K2496 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2448 Phosphorylation PRO 10567225


Q9JLN9 (Mtor) as PTM Enzyme



Substrate Site Score Source PMID
A2A9C3 (Szt2) S3230 PhosphoSitePlus 21659604
E9Q616 (Ahnak) S5525 PhosphoSitePlus 21659604
E9Q616 (Ahnak) S5536 PhosphoSitePlus 21659604
E9Q616 (Ahnak) S5553 PhosphoSitePlus 21659604
E9Q616 (Ahnak) T5571 PhosphoSitePlus 21659604
E9Q777 (Akap11) S987 PhosphoSitePlus 21659604
E9Q777 (Akap11) T1092 PhosphoSitePlus 21659604
P05627 (Jun) T242 PhosphoSitePlus 21659604
P05627 (Jun) S246 PhosphoSitePlus 21659604
P08775 (Polr2a) S1934 PhosphoSitePlus 21659604
P14873 (Map1b) S1247 PhosphoSitePlus 21659604
P14873 (Map1b) S1260 PhosphoSitePlus 21659604
P19096 (Fasn) T1029 PhosphoSitePlus 23585690
P19096 (Fasn) T1033 PhosphoSitePlus 23585690
P31750 (Akt1) S473 phospho.ELM   PhosphoSitePlus 23852728, 16221682
P35569 (Irs1) S632 PhosphoSitePlus 11287630
P35569 (Irs1) S635 PhosphoSitePlus 11287630
P42128 (Foxk1) S427 PhosphoSitePlus 21659604
P42128 (Foxk1) S431 PhosphoSitePlus 21659604
P42227 (Stat3) S727 PhosphoSitePlus 26573296
P53564 (Cux1) S882 PhosphoSitePlus 21659604
P70445 (Eif4ebp2) T37 PhosphoSitePlus 21659604
P70445 (Eif4ebp2) T41 PhosphoSitePlus 21659604
P81122 (Irs2) S616 PhosphoSitePlus 21659604
P97287 (Mcl1) T144 PhosphoSitePlus 21659604
Q3TC46 (Patl1) T194 PhosphoSitePlus 21659604
Q3UCQ1 (Foxk2) S389 PhosphoSitePlus 21659604
Q3UMB5 (Smcr8) S416 PhosphoSitePlus 21659604
Q4VGL6 (Rc3h1) S535 PhosphoSitePlus 21659604
Q5HZG4 (Taf3) S229 PhosphoSitePlus 21659604
Q60760 (Grb10) S103 PhosphoSitePlus 21659604
Q60760 (Grb10) S104 PhosphoSitePlus 21659604
Q60876 (Eif4ebp1) T35 Signor 20670887
Q60876 (Eif4ebp1) T36 PhosphoSitePlus 10942774
Q60876 (Eif4ebp1) T44 Signor 20670887
Q60876 (Eif4ebp1) T45 PhosphoSitePlus 10942774
Q60876 (Eif4ebp1) S64 PhosphoSitePlus 10942774
Q60876 (Eif4ebp1) T69 PhosphoSitePlus 10942774
Q62188 (Dpysl3) S522 PhosphoSitePlus 21659604
Q64512 (Ptpn13) S1073 PhosphoSitePlus 21659604
Q64512 (Ptpn13) S1077 PhosphoSitePlus 21659604
Q6NZJ6 (Eif4g1) T212 PhosphoSitePlus 21659604
Q6P5H2 (Nes) S919 PhosphoSitePlus 21659604
Q6PDH0 (Phldb1) S1007 PhosphoSitePlus 21659604
Q6PDH0 (Phldb1) S1009 PhosphoSitePlus 21659604
Q6PIJ4 (Nfrkb) S351 PhosphoSitePlus 21659604
Q6ZQ58 (Larp1) S743 PhosphoSitePlus 21659604
Q6ZQ58 (Larp1) S751 PhosphoSitePlus 21659604
Q6ZQH8 (Nup188) T1515 PhosphoSitePlus 21659604
Q7TQH0 (Atxn2l) T31 PhosphoSitePlus 21659604
Q7TQH0 (Atxn2l) S32 PhosphoSitePlus 21659604
Q7TT50 (Cdc42bpb) S1692 PhosphoSitePlus 21659604
Q80W47 (Wipi2) S395 PhosphoSitePlus 21659604
Q80YS6 (Afap1) S665 PhosphoSitePlus 21659604
Q80YS6 (Afap1) S666 PhosphoSitePlus 21659604
Q80YS6 (Afap1) S669 PhosphoSitePlus 21659604
Q80Z37 (Topors) S1016 PhosphoSitePlus 21659604
Q810L3 (Chfr) S231 PhosphoSitePlus 21659604
Q8BHL3 (Tbc1d10b) S643 PhosphoSitePlus 21659604
Q8BHL3 (Tbc1d10b) S647 PhosphoSitePlus 21659604
Q8BHL3 (Tbc1d10b) S650 PhosphoSitePlus 21659604
Q8BSK8 (Rps6kb1) S394 Signor 12782654
Q8BSK8 (Rps6kb1) T412 Signor 17510057, 12782654
Q8BSK8 (Rps6kb1) S434 Signor 12782654
Q8BTM8 (Flna) S1338 PhosphoSitePlus 21659604
Q8CGF1 (Arhgap29) S1040 PhosphoSitePlus 21659604
Q8CIL4 T53 PhosphoSitePlus 21659604
Q8CIL4 S67 PhosphoSitePlus 21659604
Q8K120 (Nfatc4) S168 PhosphoSitePlus 18347059
Q8K120 (Nfatc4) S170 PhosphoSitePlus 18347059
Q8K1N2 (Phldb2) S17 PhosphoSitePlus 21659604
Q8K363 (Ddx18) T101 PhosphoSitePlus 21659604
Q924W7 (Dennd2b) S30 PhosphoSitePlus 21659604
Q924W7 (Dennd2b) S32 PhosphoSitePlus 21659604
Q924W7 (Dennd2b) S42 PhosphoSitePlus 21659604
Q9JI11 (Stk4) S438 PhosphoSitePlus 25843706
Q9JLN9 (Mtor) S2481 PhosphoSitePlus   Signor 20022946
Q9Z148 (Ehmt2) S287 PhosphoSitePlus 21659604


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000050320 (mMTOR/iso:1/Phos:1) pS2448 PRO 10567225


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O70405 (Ulk1) S555 Q9JLN9 (Mtor) inhibited_association eFIP 29348566